Food For Thought

Food for Thought MicrobiomeHuman Microbiome Research

"human microbiome"

"human microbiome": Latest results from PubMed

Commensals make the most of their hosts

In this issue of Cell Host & Microbe, Brown et al. reveal a large group of genes within the human microbiome that cod...
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Forensic Analysis of Human Microbiome in Skin and Body Fluids Based on Geographic Location

High-throughput DNA sequencing technologies have facilitated the in silico forensic analysis of human microbiome. Spe...
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Does Day-to-Day Variability in Stool Consistency Link to the Fecal Microbiota Composition?

CONCLUSION: This study supports an association between stool consistency and fecal microbiota, but no effect of day-t...
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Adaptor Molecules Epitranscriptome Reprograms Bacterial Pathogenicity

The strong decoration of tRNAs with post-transcriptional modifications provides an unprecedented adaptability of this...
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Antibiotics and the Human Microbiome: A Survey of Prescribing Clinicians' Knowledge and Opinions Regarding the Link between Antibiotic-Induced Dysbiosis and Immune-Mediated Disease

Altered composition or function of the human micro- biome, termed dysbiosis, has been associated with a variety of im...
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Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health

We describe the anaerobic conversion of inositol stereoisomers to propionate and acetate by the abundant intestinal g...
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Recurrent Urinary Tract Infections: Unraveling the Complicated Environment of Uncomplicated rUTIs

Urinary tract infections (UTIs) are frequent in humans, affecting the upper and lower urinary tract. Present diagnosi...
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The bad relationship, osteo-decay and diabetes type 2 searching for a link: a literature review

The diabetes and osteoporotic metabolic diseases are characterized by a wide prevalence of the population worldwide a...
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Early-life gut microbiota and its connection to metabolic health in children: Perspective on ecological drivers and need for quantitative approach

The colonisation and development of the gut microbiota has been implicated in paediatric metabolic disorders via its ...
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From native core micriobiome to milk-oriented microbiome

The human microbiome is the full set of microorganisms (microbiota) present on and in our body. Its importance is suc...
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Characterization of low-density granulocytes in COVID-19

Severe COVID-19 is characterized by extensive pulmonary complications, to which host immune responses are believed to...
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Dietary Fibre Intervention for Gut Microbiota, Sleep, and Mental Health in Adults with Irritable Bowel Syndrome: A Scoping Review

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder affecting 4-5% of the global populati...
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Identification of Lung and Blood Microbiota Implicated in COVID-19 Prognosis

The implications of the microbiome on Coronavirus disease 2019 (COVID-19) prognosis has not been thoroughly studied. ...
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COVID-19 Lockdowns May Reduce Resistance Genes Diversity in the Human Microbiome and the Need for Antibiotics

Recently, much attention has been paid to the COVID-19 pandemic. Yet bacterial resistance to antibiotics remains a se...
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Defining the resilience of the human salivary microbiota by a 520-day longitudinal study in a confined environment: the Mars500 mission

CONCLUSIONS: The uniqueness of Mars500 mission, allowed to dampen the effect of environmental variables on salivary m...
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Interactive exploratory data analysis of Integrative Human Microbiome Project data using Metaviz

The rich data produced by the second phase of the Human Microbiome Project (iHMP) offers a unique opportunity to test...
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The human microbiome and COVID-19: A systematic review

CONCLUSION: The human fecal and respiratory tract microbiome changed in COVID-19 patients with opportunistic pathogen...
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NON-ALCOHOLIC FATTY LIVER DISEASE IN THE CONTEXT OF ALTERED GUT MICROBIOTA

CONCLUSION: Conclusions: In recent years, non-alcoholic fatty liver disease was placed among the important diseases i...
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Low-Abundant Microorganisms: The Human Microbiome's Dark Matter, a Scoping Review

Research on the human microbiome has mainly been restricted to the identification of most abundant microbiota associa...
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Food for Thought Paleo Diet 2Paleo Diet Research

paleo diet

paleo diet: Latest results from PubMed

Paleolithic Diet-Effect on the Health Status and Performance of Athletes?

The aim of this meta-analysis was to review the impact of a Paleolithic diet (PD) on selected health indicators (body...
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Therapeutic Implications of Diet in Inflammatory Bowel Disease and Related Immune-Mediated Inflammatory Diseases

Despite being a focal issue to patients, the effect of diet on adult inflammatory bowel disease (IBD) remains underex...
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Using a Paleo Ratio to Assess Adherence to Paleolithic Dietary Recommendations in a Randomized Controlled Trial of Individuals with Type 2 Diabetes

This study is a secondary analysis of a randomized controlled trial using Paleolithic diet and exercise in individual...
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Dietary protein intake, kidney function, and survival in a nationally representative cohort

CONCLUSIONS: Among participants with impaired kidney function, a higher DPI and greater HBV consumption were associat...
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A novel evolutionary-concordance lifestyle score is inversely associated with all-cause, all-cancer, and all-cardiovascular disease mortality risk

CONCLUSIONS: Our findings suggest that a more evolutionary-concordant lifestyle may be inversely associated with all-...
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At the dinner table with Adam and Eve

Parents of children with atopic dermatitis often believe that dietary factors influence the course of a child's eczem...
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Ecosystem engineering in the Quaternary of the West Coast of South Africa

Despite advances in our understanding of the geographic and temporal scope of the Paleolithic record, we know remarka...
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Alternative diets among adolescents: facts or fads?

PURPOSE OF REVIEW: With rising rates of chronic noninfectious diseases across the United States thought to be associa...
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Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies

CONCLUSIONS: This study provides evidence that the plant-based dietary patterns are associated with lowered levels of...
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How long do people stick to a diet resolution? A digital epidemiological estimation of weight loss diet persistence

CONCLUSIONS: The current study is the first of its kind to use passive surveillance data to compare the duration of a...
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Productivity loss associated with functional disability in a contemporary small-scale subsistence population

In comparative cross-species perspective, humans experience unique physical impairments with potentially large conseq...
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Short-term effects of a Paleolithic lifestyle intervention in breast cancer patients undergoing radiotherapy: a pilot and feasibility study

Evolutionary principles are rarely considered in clinical oncology. We here aimed to test the feasibility and effects...
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Early life of Neanderthals

The early onset of weaning in modern humans has been linked to the high nutritional demand of brain development that ...
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Efficacy of different dietary patterns on lowering of blood pressure level: an umbrella review

CONCLUSION: Adherence to the DASH, Nordic, and portfolio diets effectively reduced BP. Low-salt diets significantly d...
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Exploring late Paleolithic and Mesolithic diet in the Eastern Alpine region of Italy through multiple proxies

OBJECTIVES: The analysis of prehistoric human dietary habits is key for understanding the effects of paleoenvironment...
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A Fad too Far? Dietary Strategies for the Prevention and Treatment of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is a major health problem, and its prevalence has increased in recent years,...
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The Influence of Markets on the Nutrition Transition of Hunter-Gatherers: Lessons from the Western Amazon

For many centuries, hunter-gatherer societies relied on subsistence practices and traditional diets. However, forces ...
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Cycles of attention to fad diets and internet search trends by Google trends

This work aimed at identifying, describing and analyzing news content associated with Google search cycles linked to ...
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Tracing human mobility in central Europe during the Upper Paleolithic using sub-seasonally resolved Sr isotope records in ornaments

Mobility of people and goods during the Upper Paleolithic has proven difficult to reconstruct given the relative rare...
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ButterKetogenic Diet Research

"ketogenic diet"

"ketogenic diet": Latest results from PubMed

Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players

CONCLUSIONS: This is the first study investigating the effects of a KD on semi-professional soccer players. In our st...
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Very Low-Calorie Ketogenic Diet Modulates the Autonomic Nervous System Activity through Salivary Amylase in Obese Population Subjects

In obesity, to reduce visceral adipose tissue (VAT), caloric restriction is a valid strategy. Salivary amylase is an ...
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Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

A healthy regime is fundamental for the prevention of cardiovascular diseases (CVD). In inherited channelopathies, su...
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Keto-on-the-Clock: A Survey of Dietetic Care Contact Time Taken to Provide Ketogenic Diets for Drug-Resistant Epilepsy in the UK

Medical ketogenic diets (KDs) are effective yet resource-intensive treatment options for drug-resistant epilepsy (DRE...
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Ketogenic Diet, Physical Activity, and Hypertension-A Narrative Review

Several studies link cardiovascular diseases (CVD) with unhealthy lifestyles (unhealthy dietary habits, alcohol consu...
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Truths and Myths in Pediatric Migraine and Nutrition

The link between migraine and nutrition can be explored from several points of view. Lifestyle and, in particular, as...
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Effect of Diet and Dietary Components on the Composition of the Gut Microbiota

Diet and dietary components have profound effects on the composition of the gut microbiota and are among the most imp...
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The Effect of a Ketogenic Low-Carbohydrate, High-Fat Diet on Aerobic Capacity and Exercise Performance in Endurance Athletes: A Systematic Review and Meta-Analysis

A low-carbohydrate, high-fat (LCHF) diet has been proposed to enhance the fat utilization of muscle and the aerobic c...
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On the nutritional and therapeutic effects of ketone body D-β-hydroxybutyrate

D-β-hydroxybutyrate (D-3HB), a monomer of microbial polyhydroxybutyrate (PHB), is also a natural ketone body produced...
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Early infantile epileptic encephalopathy caused by PACS2 gene variation: three cases report and literature review

Objective: To explore the clinical features of three early-onset infantile epileptic encephalopathy (EIEE) patients w...
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A Machine-Generated View of the Role of Blood Glucose Levels in the Severity of COVID-19

SARS-CoV-2 started spreading toward the end of 2019 causing COVID-19, a disease that reached pandemic proportions amo...
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Obesity, inflammation and COVID-19: preventive interest of ketogenic diet?

Obesity is considered a pandemic responsible for millions of deaths worldwide for many years. At the end of 2019, the...
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NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation

Loss-of-function mutations in NEK1 gene, which encodes a serine/threonine kinase, are involved in human developmental...
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Applications of Ketogenic Diets in Patients with Headache: Clinical Recommendations

Headaches are among the most prevalent and disabling neurologic disorders and there are several unmet needs as curren...
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APOE Genotype and Alzheimer's Disease: The Influence of Lifestyle and Environmental Factors

Alzheimer's disease (AD) is the most common neurodegenerative disorder with obscure pathogenesis and no disease-modif...
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Challenges faced by people with epilepsy on ketogenic diet therapy and their caregivers during the COVID-19 pandemic in Brazil

CONCLUSIONS: People with pharmacoresistant epilepsy and undergoing KDT, as well as their caregivers, faced additional...
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Ketogenic diet for mitochondrial disease: a systematic review on efficacy and safety

CONCLUSION: Data on efficacy and safety of KD for MD is too scarce for general recommendations. KD should be consider...
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Graph Theory-Based Electroencephalographic Connectivity and Its Association with Ketogenic Diet Effectiveness in Epileptic Children

Ketogenic diet therapies (KDTs) are widely used treatments for epilepsy, but the factors influencing their responsive...
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An fMRI Investigation into the Effects of Ketogenic Medium-Chain Triglycerides on Cognitive Function in Elderly Adults: A Pilot Study

Evidence suggests that oral intake of medium-chain triglycerides (MCTs), which promote the production of ketone bodie...
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Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases

Life expectancy of humans has increased continuously up to the present days, but their health status (healthspan) was...
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Ketogenic Dietary Therapies in Patients with Autism Spectrum Disorder: Facts or Fads? A Scoping Review and a Proposal for a Shared Protocol

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with increasing incidence. An expanding body of liter...
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The Feasibility and Tolerability of Medium Chain Triglycerides in Women with a Catamenial Seizure Pattern on the Modified Atkins Diet

Ketogenic diet therapy (KDT), particularly modified Atkins diet (MAD), is increasingly recognized as a treatment for ...
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Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

Increasing age is the strongest predictor of risk of COVID-19 severity and mortality. Immunometabolic switch from gly...
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The effect of ketogenic diet on serum lipid concentrations in children with medication resistant epilepsy

CONCLUSION: Total cholesterol and triglyceride concentrations appear to increase during the first month of KD treatme...
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Body composition changes in physically active individuals consuming ketogenic diets: a systematic review

CONCLUSION: KD can promote mobilization of fat stores to reduce FM while retaining FFM. However, there is variance in...
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Novel Nutritional and Dietary Approaches to Weight Loss for the Prevention of Cardiovascular Disease: Ketogenic Diet, Intermittent Fasting, and Bariatric Surgery

PURPOSE OF REVIEW: Cardiovascular disease (CVD) is highly associated with obesity and cardiometabolic dysfunction. Th...
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The Chemistry of the Ketogenic Diet: Updates and Opportunities in Organic Synthesis

The high-fat, low-carbohydrate (ketogenic) diet has grown in popularity in the last decade as a weight loss tool. Res...
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NGS-Based Diagnosis of Treatable Neurogenetic Disorders in Adults: Opportunities and Challenges

The identification of neurological disorders by next-generation sequencing (NGS)-based gene panels has helped clinici...
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The Potential Health Benefits of the Ketogenic Diet: A Narrative Review

Considering the lack of a comprehensive, multi-faceted overview of the ketogenic diet (KD) in relation to health issu...
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Evidences for a Role of Gut Microbiota in Pathogenesis and Management of Epilepsy

Epilepsy as a chronic neurological disorder is characterized by recurrent, unprovoked epileptic seizures. In about ha...
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Obesity and Circulating Levels of Vitamin D before and after Weight Loss Induced by a Very Low-Calorie Ketogenic Diet

Background: Vitamin D plays a pivotal role in calcium and phosphorus metabolism, also influencing bone tissue. Severa...
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Reduction of Cardio-Metabolic Risk and Body Weight through a Multiphasic Very-Low Calorie Ketogenic Diet Program in Women with Overweight/Obesity: A Study in a Real-World Setting

CONCLUSIONS: The findings of a multi-center VLCKD program conducted in a real-world setting in a cohort of overweight...
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Does the size of a ketogenic diet admission group influence outcomes?

CONCLUSIONS: Admitting children in larger groups, specifically 3 children at a time, was associated with longer KD du...
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Efficacy and tolerability of a whey-based, medium-chain triglyceride-enhanced ketogenic formula in children with refractory epilepsy: A retrospective study

CONCLUSION: The WBME ketogenic formula appears to be effective and well tolerated by pediatric patients with refracto...
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Role of ketones, ketogenic diets and intermittent fasting in ICU

PURPOSE OF REVIEW: To summarize the clinical evidence for beneficial effects of ketones, ketogenic diets and intermit...
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Ketogenic Diet Suppressed T-Regulatory Cells and Promoted Cardiac Fibrosis via Reducing Mitochondria-Associated Membranes and Inhibiting Mitochondrial Function

Ketogenic diet (KD) is popular in diabetic patients but its cardiac safety and efficiency on the heart are unknown. T...
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Complementary and Alternative Medicine for the Treatment of Gliomas: Scoping Review of Clinical Studies, Patient Outcomes, and Toxicity Profiles

CONCLUSIONS: Despite widespread use, Level I or II evidence for CAM for the treatment of glioma is lacking, represent...
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Diet-Related Alterations of Gut Bile Salt Hydrolases Determined Using a Metagenomic Analysis of the Human Microbiome

The metabolism of bile acid by the gut microbiota is associated with host health. Bile salt hydrolases (BSHs) play a ...
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Evaluation of E-Health Applications for Paediatric Patients with Refractory Epilepsy and Maintained on Ketogenic Diet

E-health technologies improve healthcare quality and disease management. The aim of this study was to develop a ketog...
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Efficacy of Low-Carbohydrate Ketogenic Diet as an Adjuvant Cancer Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The role of low-carbohydrate ketogenic diet (LCKD) as an adjuvant therapy in antitumor treatment is not well establis...
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Effects of Calorie Restriction on Health Span and Insulin Resistance: Classic Calorie Restriction Diet vs. Ketosis-Inducing Diet

As the incidence of Chronic Non-Communicable Diseases (CNCDs) increases, preventive approaches become more crucial. I...
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Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade

Aberrant energy status contributes to multiple metabolic diseases, including obesity, diabetes, and cancer, but the u...
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DNM1L gene variant caused encephalopathy, lethal, due to defective mitochondrial peroxisomal fission 1: three cases report and literature review

Objective: To investigate the clinical characteristics of R403C variant in DNM1L gene caused encephalopathy, lethal, ...
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Clinical efficacy of eucaloric ketogenic nutrition in the COVID-19 cytokine storm: A retrospective analysis of mortality and intensive care unit admission

CONCLUSIONS: These results show a possible therapeutic role of an EKD in the clinical management of COVID-19. Current...
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Gut flora and metabolism are altered in epilepsy and partially restored after ketogenic diets

OBJECTIVE: The aim of this study was to investigate the composition of the intestinal microbiota and its association ...
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Efficacy and safety of corpus callosotomy and ketogenic diet in children with Lennox Gastaut syndrome: a systematic review and meta-analysis

CONCLUSION: CC is more efficacious than KD in reducing seizure frequency in patients with LGS, although it has relati...
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Enemy or ally? Fasting as an essential regulator of immune responses

Nutrition is essential for supplying an organism with sufficient energy to maintain its bodily functions. Apart from ...
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