Food For Thought

Food for Thought MicrobiomeHuman Microbiome Research

"human microbiome"

"human microbiome": Latest results from PubMed

Islet autoantibody seroconversion in type-1 diabetes is associated with metagenome-assembled genomes in infant gut microbiomes

The immune system of some genetically susceptible children can be triggered by certain environmental factors to produ...
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Super-taxon in human microbiome are identified to be associated with colorectal cancer

CONCLUSIONS: Our work shows that proposed approaches are effective to study the microbiota-disease relation taking in...
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Halophilic Archaea <em>Halorhabdus Rudnickae</em> and <em>Natrinema Salaciae</em> Activate Human Dendritic Cells and Orient T Helper Cell Responses

Halophilic archaea are procaryotic organisms distinct from bacteria, known to thrive in hypersaline environments, inc...
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Study on the dynamic changes of oral microbiota in type 2 diabetes patients with periodontitis after initial periodontal therapy

Objectives: To clarify the effect of initial periodontal therapy on the dynamic changes of oral (saliva, dorsal tongu...
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Fecal microbiota in congenital chloride diarrhea and inflammatory bowel disease

CONCLUSIONS: Fecal microbiota in CLD is different from that of healthy subjects or Crohn´s disease. Unexpectedly, no ...
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The influence of perceived stress on the human microbiome

OBJECTIVE: Microbial dysbiosis, a shift from commensal to pathogenic microbiota, is often associated with mental heal...
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Unraveling function and diversity of bacterial lectins in the human microbiome

The mechanisms by which commensal organisms affect human physiology remain poorly understood. Lectins are non-enzymat...
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MeShClust v3.0: high-quality clustering of DNA sequences using the mean shift algorithm and alignment-free identity scores

CONCLUSIONS: These results demonstrate the high quality of clusters produced by MeShClust v3.0 and its ability to app...
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Metagenomic assembled plasmids of the human microbiome vary across disease cohorts

We compiled a human metagenome assembled plasmid (MAP) database and interrogated differences across multiple studies ...
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The sanitary indoor environment-a potential source for intact human-associated anaerobes

A healthy human microbiome relies on the interaction with and exchange of microbes that takes place between the human...
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Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes

Gut microbiota metabolism of dietary compounds generates a vast array of microbiome-dependent metabolites (MDMs), whi...
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A 4-Week Diet Low or High in Advanced Glycation Endproducts Has Limited Impact on Gut Microbial Composition in Abdominally Obese Individuals: The deAGEing Trial

Dietary advanced glycation endproducts (AGEs), abundantly present in Westernized diets, are linked to negative health...
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Association Study of Anticitrullinated Peptide Antibody Status with Clinical Manifestations and SNPs in Patients Affected with Rheumatoid Arthritis: A Pilot Study

CONCLUSION: Remained 11 earlier identified significantly associated in Caucasian and Asian population SNPs were not r...
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Gut microbiota predicts body fat change following a low-energy diet: a PREVIEW intervention study

CONCLUSIONS: The gut microbiota and individual taxa were significantly influenced by the LED intervention and correla...
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The standardisation of the approach to metagenomic human gut analysis: from sample collection to microbiome profiling

In recent years, the number of metagenomic studies increased significantly. Wide range of factors, including the trem...
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Naturalization of the microbiota developmental trajectory of Cesarean-born neonates after vaginal seeding

CONCLUSIONS: The results of this observational study prompt urgent randomized clinical trials to test whether microbi...
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Generation and application of pseudo-long reads for metagenome assembly

CONCLUSIONS: PLR-GEN can be used to generate artificial long read sequences without spending extra sequencing cost, t...
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Food for Thought Paleo Diet 2Paleo Diet Research

paleo diet

paleo diet: Latest results from PubMed

Dietary Approaches and Health Outcomes: An Evidence Analysis Center Scoping Review

Appropriate diet can prevent, manage, or reverse noncommunicable health conditions such as obesity, cardiovascular di...
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Controversial Dietary Patterns: A High Yield Primer for Clinicians

In cardiology clinic visits, the discussion of optimal dietary patterns for prevention and management of cardiovascul...
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Associations of Evolutionary-Concordance Diet and Lifestyle Pattern Scores with Incident, Sporadic Colorectal Adenoma in a Pooled Case-Control Study

Differences in diet and lifestyle relative to those of our Paleolithic-era ancestors may explain current high inciden...
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The importance of nutrition in pregnancy and lactation: lifelong consequences

Most women in the United States do not meet the recommendations for healthful nutrition and weight before and during ...
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The Relationship between Modern Fad Diets and Kidney Stone Disease: A Systematic Review of Literature

CONCLUSIONS: Few studies evaluated the direct relationship between modern fad diets and KSD. In general, the reductio...
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The energetics of uniquely human subsistence strategies

The suite of derived human traits, including enlarged brains, elevated fertility rates, and long developmental period...
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Reconstructing Neanderthal diet: The case for carbohydrates

Evidence for plants rarely survives on Paleolithic sites, while animal bones and biomolecular analyses suggest animal...
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Pastoral subsistence and mounted fighting in the Eastern Tianshan Mountain region: New insights from the Shirenzigou worked bone assemblage

Situated at a geographic crossroads, the eastern Tianshan Mountain region in northwest China is crucial to understand...
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Whole-diet interventions and cardiovascular risk factors in postmenopausal women: A systematic review of controlled clinical trials

CONCLUSION: Current evidence suggests that diet may affect levels of some lipid profile markers, glycemic indices, an...
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Change in Micronutrient Intake among People with Relapsing-Remitting Multiple Sclerosis Adapting the Swank and Wahls Diets: An Analysis of Weighed Food Records

The low-saturated fat (Swank) and modified Paleolithic elimination (Wahls) diets have shown promise for MS symptoms; ...
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A score appraising Paleolithic diet and the risk of cardiovascular disease in a Mediterranean prospective cohort

CONCLUSIONS: Our findings suggest that the PaleoDiet may have cardiovascular benefits in participants from a Mediterr...
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Factors controlling iodine enrichment in a coastal plain aquifer in the North Jiangsu Yishusi Plain, China

Iodine is an essential micronutrient in the human diet and an appropriate human iodine intake level is important for ...
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Early line and hook fishing at the Epipaleolithic site of Jordan River Dureijat (Northern Israel)

Nineteen broken and complete bone fish hooks and six grooved stones recovered from the Epipaleolithic site of Jordan ...
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Early Pleistocene faunivorous hominins were not kleptoparasitic, and this impacted the evolution of human anatomy and socio-ecology

Humans are unique in their diet, physiology and socio-reproductive behavior compared to other primates. They are also...
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Comparative study of B content and δ<sup>11</sup> B in the enamel of isolated teeth from brothers in the same family

CONCLUSIONS: The experimental data confirmed the relationship between the information of B (B content and δ^(11) B) i...
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Effects of Evolution, Ecology, and Economy on Human Diet: Insights from Hunter-Gatherers and Other Small-Scale Societies

We review the evolutionary origins of the human diet and the effects of ecology economy on the dietary proportion of ...
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Hunter-Gatherers in context: Mammal community composition in a northern Tanzania landscape used by Hadza foragers and Datoga pastoralists

In many regions of sub Saharan Africa large mammals occur in human-dominated areas, yet their community composition a...
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ButterKetogenic Diet Research

"ketogenic diet"

"ketogenic diet": Latest results from PubMed

Cognitive, Sleep, and Autonomic Responses to Induction of a Ketogenic Diet in Military Personnel: A Pilot Study

BACKGROUND: This pilot study examined the effect of a 2-wk ketogenic diet (KD) compared with a carbohydrate (CHO) die...
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Targeted gut microbiota manipulation attenuates seizures in a model of infantile spasms syndrome

Infantile spasms syndrome (IS) is a devastating early-onset epileptic encephalopathy associated with poor neurodevelo...
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The Ketogenic Diet and Alzheimer's Disease

CONCLUSION: Most current studies are small, often uncontrolled, and only look at the short-term effects of ketosis on...
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Possible Nonneurological Health Benefits of Ketogenic Diet: Review of Scientific Reports over the Past Decade

The ketogenic diet (KD) has been used since the 1920s as a therapy for drug-resistant epilepsy. Due to the beneficial...
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Could the ketogenic diet induce a shift in thyroid function and support a metabolic advantage in healthy participants? A pilot randomized-controlled-crossover trial

CONCLUSIONS: Although the diets were isocaloric and physical activity and resting metabolic rate remained constant, t...
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Ketogenic dietary therapies for epilepsy: Experience in 160 patients over 18 years

CONCLUSIONS: KDT are effective for refractory epilepsy in children. However, adverse effects are frequent, and it may...
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CDKL5 Deficiency Disorder-Related Epilepsy: A Review of Current and Emerging Treatment

Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a developmental and epileptic encephalopathy with...
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Dietary influences on symptomatic and non-symptomatic toxicities during cancer treatment: A narrative review

The general nutritional status of cancer patients could be a central determinant of cancer treatment-related toxicity...
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The effect of low-carbohydrate ketogenic diet in the management of obesity compared with low caloric, low-fat diet

CONCLUSION: LCKD seems superior to LCLF in weight, fat mass and visceral fat reduction. In addition, this diet does n...
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The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation

Elevating blood ketones may enhance exercise capacity and modulate adaptations to exercise training; however, these e...
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The effectiveness of the ketogenic diet in drug-resistant childhood epilepsy

CONCLUSION: Ketogenic diet treatment appears to be effective in about two-thirds of children with various types of dr...
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Clinical implementation of ketogenic diet in children with drug-resistant epilepsy: Advantages, disadvantages, and difficulties

CONCLUSIONS: Despite increasing availability and good efficacy, long-term adherence to KD was difficult. Compliance i...
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Quantitative Three-Dimensional Gait Evaluation in Patients With Glucose Transporter 1 Deficiency Syndrome

CONCLUSIONS: 3DGA has potential for quantifying the characteristics of gait pathology and its improvement with dietar...
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Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet

BACKGROUND: Recently, studies have suggested a role for the gut microbiota in epilepsy. Gut microbial changes during ...
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Core outcome set development for childhood epilepsy treated with ketogenic diet therapy: Results of a scoping review and parent interviews

CONCLUSION: Little consistency exists in the outcomes used in childhood epilepsy and KD research. Those traditionally...
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Gut-based manipulations spur hippocampal mitochondrial bioenergetics in a model of pediatric epilepsy

A growing body of evidence supports a role of the gut microbiota in regulating diverse physiological processes, inclu...
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Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome <em>Via</em> B-hydroxybutyrate and Fibroblast Growth Factor 21

A ketogenic diet (KD) is known to have beneficial health effects. Various types of KD interventions have been applied...
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Effects of Classic Ketogenic Diet in Children with Refractory Epilepsy: A Retrospective Cohort Study in Kingdom of Bahrain

Background: The classic ketogenic diet (cKD) has been used worldwide as an effective therapy for children with drug-r...
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Ketogenic Diet and Weight Loss: Is There an Effect on Energy Expenditure?

A dysregulation between energy intake (EI) and energy expenditure (EE), the two components of the energy balance equa...
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The Therapeutic Role of Ketogenic Diet in Neurological Disorders

The ketogenic diet (KD) is a high-fat, low-carbohydrate and adequate-protein diet that has gained popularity in recen...
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Nutrition interventions in congenital disorders of glycosylation

Congenital disorders of glycosylation (CDG) are a group of more than 160 inborn errors of metabolism affecting multip...
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Case Report: Hypercholesterolemia "Lean Mass Hyper-Responder" Phenotype Presents in the Context of a Low Saturated Fat Carbohydrate-Restricted Diet

Emerging evidence suggests that "leanness" and good metabolic health markers may predict larger increases in LDL chol...
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Head circumference in glucose transporter 1 deficiency syndrome: Normal for individuals, abnormal as a group

In the literature, microcephaly is considered as part of the classical phenotype of glucose transporter 1 deficiency ...
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The effect of the ketogenic diet on leptin, chemerin and resistin levels in children with epilepsy

CONCLUSIONS: Modification of pro-inflammatory adipocytokine levels is potentially one of the mechanisms of anticonvul...
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Migraine and Diet: Updates in Understanding

PURPOSE OF REVIEW: We explore recent developments in the prevention and treatment of migraine through dietary interve...
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Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth

CONCLUSIONS: Ketogenic diet sensitizes murine pancreatic cancer tumors to cytotoxic chemotherapy. Based on these data...
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Phase II study of ketogenic diets in relapsing multiple sclerosis: safety, tolerability and potential clinical benefits

CONCLUSION: KDs are safe and tolerable over a 6-month study period and yield improvements in body composition, fatigu...
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Telemedicine- versus outpatient-based initiation and management of ketogenic diet therapy in children with drug-resistant epilepsy during the COVID-19 pandemic

CONCLUSIONS: Our results support the feasibility and safety of initiating and management of KDT by telemedicine. Pati...
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Ketogenic Diet and Cardiac Substrate Metabolism

The ketogenic diet (KD) entails a high intake of fat, moderate intake of protein, and a very limited intake of carboh...
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Ketogenic Diet Consumption Inhibited Mitochondrial One-Carbon Metabolism

Given the popularity of ketogenic diets, their potential long-term consequences deserve to be more carefully monitore...
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Efficacy of Nutritional Strategies on the Improvement of the Performance and Health of the Athlete: A Systematic Review

Evidence shows that the use of food strategies can impact health, but a clear consensus about how the effects of diff...
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Seizures and Epilepsy in Childhood

PURPOSE OF REVIEW: This article highlights basic concepts of seizures and epilepsy in pediatric patients, as well as ...
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Effects of ketosis on cocaine-induced reinstatement in male mice

In recent years, the benefits of the ketogenic diet (KD) on different psychiatric disorders have been gaining attenti...
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The metabolic basis of epilepsy

The brain is a highly energy-demanding organ and requires bioenergetic adaptability to balance normal activity with p...
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It's What and When You Eat: An Overview of Transcriptional and Epigenetic Responses to Dietary Perturbations in Pancreatic Islets

Our ever-changing modern environment is a significant contributor to the increased prevalence of many chronic disease...
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Comparison of the Impact of the Mediterranean Diet, Anti-Inflammatory Diet, Seventh-Day Adventist Diet, and Ketogenic Diet Relative to Cognition and Cognitive Decline

PURPOSE OF REVIEW: Increasing evidence points toward the importance of diet and its impact on cognitive decline. This...
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About gladiators and a sacred disease

In this special edition of the Biomedical Journal the reader gains an insight into drug-resistant epilepsy and accord...
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Diagnostic and Clinical Manifestation Differences of Glucose Transporter Type 1 Deficiency Syndrome in a Family with SLC2A1 Gene Mutation

Glucose transporter type 1 deficiency syndrome is a rare genetic disease that manifests neurological symptoms such as...
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Effect of Dietary Intake Through Whole Foods on Cognitive Function: Review of Randomized Controlled Trials

PURPOSE OF REVIEW: This review evaluated recent randomized controlled trials (RCTs) examining the chronic intake of w...
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Effects of dietary components on intestinal short-chain fatty acids (SCFAs) synthesis in healthy adult persons following a ketogenic diet

CONCLUSIONS: High consumption of cruciferous and leaf vegetables, berries and nuts on a ketogenic diet may have a pos...
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Non-pharmacological treatments for pediatric refractory epilepsies

INTRODUCTION: Antiseizure medications (ASMs) are the primary treatment option for epilepsies of wide etiologies, howe...
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The Efficacy and Safety of Ketogenic Diets in Drug-Resistant Epilepsy in Children and Adolescents: a Systematic Review of Randomized Controlled Trials

PURPOSE OF REVIEW: Drug-resistant epilepsy represents around one-quarter of epilepsies worldwide. Although ketogenic ...
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Study of paediatric patients with the clinical and biochemical phenotype of glucose transporter type 1 deficiency syndrome

CONCLUSIONS: GLUT1 deficiency syndrome may be caused by mutations to genes other than SLC2A1 in patients with compati...
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Lactation ketoacidosis induced by breastfeeding while on a ketogenic diet

Lactation ketoacidosis is a very rare cause of metabolic acidosis in breastfeeding patients. We present a case of a 3...
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