Food For Thought

The immune system (IS) is commonly understood as a system composed of specific cells and tissues that have evolved to...

Similarity between candidate drug targets and human proteins is commonly assessed to minimize the occurrence of side ...

Through the Human Microbiome Project, research on human-associated microbiomes has been conducted in various fields. ...

Early life gut microbiota is being increasingly recognized as a major contributor to short and/or long-term human hea...

Tuberculosis, primarily caused by Mycobacterium tuberculosis, is an airborne lung disease and continues to pose a sig...

Oncolytic viruses (OVs) hold promise for cancer treatment. However, the antitumor efficacy is limited. Microbiota pla...

CONCLUSIONS: Persistent symptoms in PCC are multifactorial and not directly linked to peripheral blood cell gene expr...

The human microbiome plays a crucial role in modulating health and disease susceptibility through a complex network o...

The human microbiome exerts tremendous influence on maintaining a balance between human health and disease. High-thro...

The human microbiome, a complex ecosystem of microbial communities, plays a crucial role in physiological processes, ...

In recent years, we have witnessed a rapidly growing interest in the intricate communications between intestinal micr...

Protein-level investigations into the human microbiome provide insights into active microbial functions. Recently, Va...

The human microbiome plays a pivotal role in the field of cancer immunotherapy. The microbial communities that inhabi...

The human microbiome produces diverse metabolites that influence host health, yet the chemical landscape of ribosomal...

The human microbiome, a complex ecosystem of microorganisms inhabiting the body, plays a critical role in human healt...

Inflammatory bowel disease (IBD) refers to chronic, recurrent inflammatory intestinal disorders, primarily including ...

The human microbiome plays a vital role in maintaining human homeostasis, acting as a key regulator of host immunity ...

BACKGROUND: Epigenetic regulation of gene expression and host defense is well established in microbial communities, w...

CONCLUSION: The overall findings suggest that these bacteriophages are potential candidates for phage therapy in trea...

Oral and systemic human health depend on the symbiotic relationship between the human host and its microbiome. As the...

INTRODUCTION: This study aimed to describe breastfeeding attitudes among health care personnel, as well as breastfeed...

Background: Cardiometabolic comorbidities are common in multiple sclerosis (MS), and lifestyle interventions are effe...

Franchthi Cave, in the Greek Peloponnese, is a well-known Paleolithic, Mesolithic and Neolithic site, with several hu...

Nutritional approach has been intensely investigated in inflammatory bowel disease (IBD) patients, but, despite many ...

Cancer is currently one of the biggest public health challenges worldwide, ranking as the second leading cause of dea...

Diabetes is a metabolic disease with a high worldwide prevalence and an important factor in mortality and disability ...

Understanding chronic kidney disease (CKD) through the lens of evolutionary biology highlights the mismatch between o...

The Wahls diet is a modified Paleolithic diet that emphasizes dark green leafy vegetables, colorful fruits, high-qual...

Adopting a healthy dietary pattern may be an initial step in combating inflammation-related chronic diseases; however...

PURPOSE OF REVIEW: Glioma is the most common type of brain cancer, associated with a high mortality rate. Diet is one...

CONCLUSIONS: We found no leptin binding inhibition after the Paleolithic or diabetes diet, possibly due to its abolis...

CONCLUSION: The Paleolithic diet may be used as a nutritional therapeutic protocol in those with HT with who have com...

OBJECTIVES: This study presents biological affinities between the last hunter-fisher-gatherers and first food-produci...

CONCLUSIONS: Using multiple dental parameters to examine the oral health of premodern individuals can provide useful ...

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful inflammatory lesions,...

The study of spatial (paleo)ecology in mammals is critical to understand how animals adapt to and exploit their envir...

CONCLUSIONS: Our research indicates that adhering to a Paleolithic diet, either alone or in conjunction with lifestyl...

Breast cancer (BC) is the most predominant malignancy in Arab women in the Middle East, and yearly increases in occur...

CONCLUSION: Our findings showed that multifunctional RCT diets have differential role in managing low-grade inflammat...

Numerous diets for losing weight, building strength, and managing a range of cardiovascular, neurologic, and skin dis...

Tumor metabolism has emerged as a critical target in cancer therapy, revolutionizing our understanding of how cancer ...

In refractory epilepsy and inherited metabolic disorders, Ketogenic Dietary Therapies (KDT) are established non-pharm...

CONCLUSIONS: VLCKD significantly improved PsA activity and metabolic health. Patients with a higher BMI and less cont...

PURPOSE OF REVIEW: This review was conducted to discuss the etiology of autism in the light of current information, t...

Psoriasis is a chronic immune-mediated skin disease characterized by cytokine dysregulation. Pro-inflammatory mediato...

Background: Tirzepatide (TZP), a unimolecular dual agonist targeting glucose-dependent insulinotropic polypeptide and...

The ketogenic diet (KD) is a dietary intervention comprising a high-fat, low-carbohydrate, and moderate-protein intak...

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major cause of chronic liver dysfunction worldw...

CONCLUSIONS: The relationship between dietary interventions and TMAO concentration remains controversial. While certa...

There are relatively few studies related to new-onset refractory status epilepticus (NORSE), in which patients with c...

PURPOSE OF REVIEW: This narrative review comprehensively analyzes VLEKT as an advanced nutritional strategy for obesi...

CONCLUSION: CR and CR + EX demonstrated the most positive effects on cardiovascular health indicators. In contrast, 5...

Epilepsy with myoclonic-atonic seizures is a childhood-onset epilepsy syndrome characterised by a range of seizure ty...

CONCLUSIONS: Twelve months of KDT can reduce monthly seizure frequency and improve mood/behavioral disturbances in pa...

Approximately 30-40% of individuals with epilepsy develop drug-resistant epilepsy (DRE), a condition associated with ...

PURPOSE OF REVIEW: This review synthesizes the latest updates in the literature on the connection between fasting and...

Increasing evidence suggests cardiac function improves in healthy and failing hearts alongside circulating ketones (1...

PURPOSE OF REVIEW: A deeper understanding of the communication network between the gut microbiome and the central ner...

Intermittent fasting (IF) and ketogenic diets (KDs) have recently attracted much attention in the scientific literatu...

Dyslipidemia, characterized by abnormal blood lipid levels, is a major public health concern due to its association w...

Background/Objectives: The increasing use of social media for sharing health and diet experiences presents new opport...

Acetyl-CoA Synthetase Short Chain Family Member-1 (ACSS1) catalyzes the ligation of acetate and coenzyme A to generat...

PURPOSE OF REVIEW: The ketogenic diet (KD) has gained clinical attention for its potential benefits in weight loss an...

Diabetic kidney disease (DKD) is the main cause of end-stage renal disease. Ketogenic diets (KD) is a high-fat, low-c...

Neonates primarily rely on innate immune defense, yet their inflammatory responses are usually restricted compared to...

Diabetic Kidney Disease (DKD) is a common and serious complication of diabetes, particularly Type 2 Diabetes Mellitus...

CONCLUSIONS: The clinical manifestations of Glut1DS primarily include seizures, movement disorders, and developmental...

The increasing morbidity and mortality of dementia places a significant burden on society in economic, social and hea...

CONCLUSIONS: Implementing a KD in patients with mental disorders seems to be a feasible and well-tolerated approach, ...

PURPOSE OF REVIEW: The purpose of this review is to present current evidence on the multifaceted approach required fo...

Ketogenic diet (KD) therapy is an effective treatment for children with refractory epilepsy. Concurrent treatment wit...

CONCLUSION: In conclusion, RES leads to significant reduction in costs 2 years post-surgery. History of RES and ketog...

Chronic kidney disease (CKD) is becoming increasingly common, and adequate nutrition is essential in the management o...

CONCLUSION: Sex is not yet a well-explored prognostic factor for outcomes following childhood epilepsy, though some s...

De novo lipogenesis (DNL) is a metabolic pathway that converts carbohydrates into fatty acids, primarily occurring in...

Background: Obesity impairs renal function through direct mechanisms, such as proinflammatory adipocytokine productio...

CONCLUSION: Type 2 diabetes prevention and treatment is crucial in this widespread disease. The first-line treatment ...

Mitochondrial diseases (MDs) are genetic disorders with diverse phenotypes that affect high-energy-demand organs, not...

CONCLUSIONS: Very low carbohydrate ketogenic diets are generally safe with low rates of IAK, including DKA, in people...

CONCLUSIONS: Barriers and facilitators for children and young people who are considering starting KDT, or who are cur...

CONCLUSIONS: OPN levels were reduced after VLCKD and severely increased after BS. Therefore, it could be a biomarker ...

Colorectal cancer (CRC) patients have been shown to possess an altered gut microbiome. Diet is a well-established mod...

Weight loss (WL) has an important role in managing obesity and type 2 diabetes, but preserving lean body mass (LBM) d...

CONCLUSIONS: Although more expensive than a common diet, VLEKT should be seen not only as a dietary method for losing...

CONCLUSION: Nutrition, dietary strategies, exercise, lifestyle and environment play an important role in the preventi...

CONCLUSION: The only prevention for SPPE is through vaccination. Several collaborative efforts have been made with WH...

Ketogenic diets (KDs) are recommended as precision therapy for glucose transporter 1 deficiency syndrome (GLUT-1 DS) ...

CONCLUSIONS: The management of FIRES in children is challenging, with limited effectiveness of most currently practic...

OBJECTIVE: Many patients with epilepsy are unable to achieve optimal seizure control with medical therapy. This artic...

A previously normal adolescent boy presented with a new-onset super refractory status epilepticus of unknown cause af...