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Food For Thought

Food for Thought MicrobiomeHuman Microbiome Research

"human microbiome"

"human microbiome": Latest results from PubMed

Cardiometabolic Effects of Omnivorous vs Vegan Diets in Identical Twins: A Randomized Clinical Trial

CONCLUSIONS AND RELEVANCE: In this randomized clinical trial of the cardiometabolic effects of omnivorous vs vegan di...
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Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping

The recently observed circadian oscillations of the intestinal microbiota underscore the profound nature of the human...
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Gut Microbiota and Bacterial Translocation in the Pathogenesis of Liver Fibrosis

Cirrhosis is the end result of liver fibrosis in chronic liver diseases. Studying the mechanisms of its development a...
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Multi-site microbiota alteration is a hallmark of kidney stone formation

CONCLUSIONS: We conclude that multi-site microbiota alteration is a hallmark of SF, and KSD treatment should consider...
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HPV co-infections with other pathogens in cancer development: A comprehensive review

High-risk human papillomaviruses (HR-HPVs) cause various malignancies in the anogenital and oropharyngeal regions. Ab...
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Effects of gut microbiome and obesity on the development, progression and prevention of cancer (Review)

Cancer is one of the leading causes of death worldwide and it is estimated that the mortality rate of cancer will inc...
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Exploring the Impact of Tobacco Usage on Microbiome Dysbiosis and Associated Health Risks: A Comprehensive Review of Recent Advancements and Future Directions

All over the world, tobacco usage is quickly expanding. Though it presents a major health risk and is anticipated to ...
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Wastewater from healthcare centers in Burkina Faso is a source of ESBL, AmpC-β-lactamase and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae

CONCLUSIONS: This study showed that wastewater from healthcare centers constitutes a reservoir of multidrug-resistant...
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Systematic mining of the human microbiome identifies antimicrobial peptides with diverse activity spectra

Human-associated bacteria secrete modified peptides to control host physiology and remodel the microbiota species com...
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Leveraging circulating microbiome signatures to predict tumor immune microenvironment and prognosis of patients with non-small cell lung cancer

CONCLUSION: A circulating MAPS prediction model was constructed successfully and showed great prognostic value for NS...
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Williams-Beuren syndrome shapes the gut microbiota metaproteome

Williams-Beuren syndrome (WBS) is a rare genetic neurodevelopmental disorder with multi-systemic manifestations. The ...
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The Human Microbiome and Its Role in Musculoskeletal Disorders

Musculoskeletal diseases (MSDs) are characterized as injuries and illnesses that affect the musculoskeletal system. M...
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Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions

The Segatella copri (formerly Prevotella copri) complex (ScC) comprises taxa that are key members of the human gut mi...
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Rational probe design for efficient rRNA depletion and improved metatranscriptomic analysis of human microbiomes

The microbiota that colonize the human gut and other tissues are dynamic, varying both in composition and functional ...
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Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity

Leishmania braziliensis is a parasitic infection that can result in inflammation and skin injury with highly variable...
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The importance of the human microbiome for mental health

Many common diseases including psychiatric disorders show characteristic alterations in the microbiome. Preclinical s...
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Oral microbiome characterization in oral mucositis patients-A systematic review

CONCLUSION: Our review indicates that cancer treatment can significantly alter the oral microbiome, with more pronoun...
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Pan-cancer spatially resolved single-cell analysis reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment

Cancer-associated fibroblasts (CAFs) are a heterogeneous cell population that plays a crucial role in remodeling the ...
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Food for Thought Paleo Diet 2Paleo Diet Research

paleo diet

paleo diet: Latest results from PubMed

Impact of Paleo Diet on Body Composition, Carbohydrate and Fat Metabolism of Professional Handball Players

The Paleo diet (PD) involves a restriction of carbohydrates and increased fat content (35% energy from carbohydrates,...
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Adherence to the Paleolithic diet and Paleolithic-like lifestyle reduce the risk of colorectal cancer in the United States: a prospective cohort study

CONCLUSIONS: Our findings suggest that adhering to the PD and PLL could be a new option to reduce CRC risk.
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Hunter-gatherer diets and activity as a model for health promotion: Challenges, responses, and confirmations

Beginning in 1985, we and others presented estimates of hunter-gatherer (and ultimately ancestral) diet and physical ...
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Comparing measured dietary variation within and between tropical hunter-gatherer groups to the Paleo Diet

CONCLUSIONS: The ethnographic evidence from tropical foragers refutes the concept of circumscribed macronutrient rang...
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Climate-driven habitat shifts of high-ranked prey species structure Late Upper Paleolithic hunting

Changing climates in the past affected both human and faunal population distributions, thereby structuring human diet...
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The Impact of Westernization on the Insulin/IGF-I Signaling Pathway and the Metabolic Syndrome: It Is Time for Change

The metabolic syndrome is a cluster of overlapping conditions resulting in an increased incidence of type 2 diabetes,...
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Popular fad diets: An evidence-based perspective

Despite the emergence of stronger nutritional science over the past two decades, fad diets remain highly popular. How...
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Popular diets as selected by adults in the United States show wide variation in carbon footprints and diet quality

CONCLUSIONS: Our results highlight the nuances when evaluating the nutritional quality of diets and their carbon foot...
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An assessment of the impact of cross-cultural variation in plant macronutrients on the recommendations of the Paleo Diet

CONCLUSIONS: The estimated whole-diet macronutrient percentages that form the basis of the Paleo Diet's macronutrient...
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Modern Diets and the Health of Our Planet: An Investigation into the Environmental Impacts of Food Choices

Popular modern diets are often seen as a panacea for improving health and promoting weight reduction. While there is ...
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Palaeolithic diet score and risk of breast cancer among postmenopausal women overall and by hormone receptor and histologic subtypes

CONCLUSIONS: High adherence to a PD characterised by fruit, vegetables, nuts, fish, and lean meat and limited in dair...
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Dietary Patterns and Non-Communicable Disease Biomarkers: A Network Meta-Analysis and Nutritional Geometry Approach

Quantitative rankings of multiple dietary patterns for their effects on non-communicable disease (NCD) biomarkers is ...
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Isolated bilateral lateral geniculate body necrosis following acute pancreatitis: A rare cause of bilateral loss of vision in a young female

Sudden bilateral visual loss because of bilateral lateral geniculate body (LGB) necrosis is a very rare entity. The m...
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Effects of different dietary interventions in multiple sclerosis: a systematic review of evidence from 2018 to 2022

BACKGROUND: Nutrition is an important risk factor for both Multiple sclerosis (MS) development and post-diagnosis dis...
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Efficacy of Diet on Fatigue and Quality of Life in Multiple Sclerosis: A Systematic Review and Network Meta-analysis of Randomized Trials

BACKGROUND AND OBJECTIVE: Emerging evidence suggests a role for diet in multiple sclerosis (MS) care; however, owing ...
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Feeding the Brain: Effect of Nutrients on Cognition, Synaptic Function, and AMPA Receptors

In recent decades, traditional eating habits have been replaced by a more globalized diet, rich in saturated fatty ac...
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Nutrition and Health in Human Evolution-Past to Present

Anyone who wants to understand the biological nature of humans and their special characteristics must look far back i...
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Developing and Piloting a Novel Ranking System to Assess Popular Dietary Patterns and Healthy Eating Principles

A multitude of weight loss diets exist. However, no one diet has been proven to be superior, despite their claims. Re...
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ButterKetogenic Diet Research

"ketogenic diet"

"ketogenic diet": Latest results from PubMed

Beneficial effects of ketogenic diet for Alzheimer's disease management

Alzheimer's disease (AD) is a neurodegenerative disease that affects almost 1 million people in France and 55 million...
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Ketogenic Diet Regulates Cardiac Remodeling and Calcium Homeostasis in Diabetic Rat Cardiomyopathy

A ketogenic diet (KD) might alleviate patients with diabetic cardiomyopathy. However, the underlying mechanism remain...
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Nutritional Approach in Selected Inherited Metabolic Cardiac Disorders-A Concise Summary of Available Scientific Evidence

Inborn errors of metabolism (IMDs) are a group of inherited diseases that manifest themselves through a myriad of sig...
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The Real-Life Use of a Protein-Sparing Modified Fast Diet by Nasogastric Tube (ProMoFasT) in Adults with Obesity: An Open-Label Randomized Controlled Trial

CONCLUSION: The ProMoFasT is more effective in improving body composition and glucometabolic markers than the same di...
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Ketogenic therapies in Parkinson's disease, Alzheimer's disease, and mild cognitive impairment: An integrative review

CONCLUSION: Ketogenic therapies have promise in PD, AD, and MCI for symptom improvement although larger studies are n...
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Does the ketogenic diet improve neurological disorders by influencing gut microbiota? A systematic review

CONCLUSION: The KD prescribed in neurological patients has effectively altered the GM composition and GM-derived meta...
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Classic ketogenic diet versus further antiseizure medicine in infants with drug-resistant epilepsy (KIWE): a UK, multicentre, open-label, randomised clinical trial

BACKGROUND: Many infancy-onset epilepsies have poor prognosis for seizure control and neurodevelopmental outcome. Ket...
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Ketosis Suppression and Ageing (KetoSAge): The Effects of Suppressing Ketosis in Long Term Keto-Adapted Non-Athletic Females

Most studies on ketosis have focused on short-term effects, male athletes, or weight loss. Hereby, we studied the eff...
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Nutritional Intervention in Cushing's Disease: The Ketogenic Diet's Effects on Metabolic Comorbidities and Adrenal Steroids

CONCLUSIONS: the current study confirms that a ketogenic diet is effective in improving metabolic disorders in CD and...
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The Implication of Nutrition on the Prevention and Improvement of Age-Related Sarcopenic Obesity: A Systematic Review

CONCLUSION: Studies suggest that dietary factors, such as overall dietary quality, appropriate intake of calories and...
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Opposite effects of low-carbohydrate high-fat diet on metabolism in humans and mice

CONCLUSIONS: Lower carbohydrate intake contributed to lower energy intake and improved metabolism in humans. In mice,...
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Experimental hemodialysis in diet-induced ketosis and the potential use of dialysis as an adjuvant cancer treatment

Numerous in vivo studies on the ketogenic diet, a diet that can induce metabolic conditions resembling those followin...
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Ketogenic Diet and the Skin

In dermatology, the role of dietary modifications as a means to manage or prevent skin disorders has recently gained ...
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Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD-a randomized controlled trial

Ketogenic dietary interventions (KDIs) are beneficial in animal models of autosomal-dominant polycystic kidney diseas...
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The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans

The PNPLA3 I148M variant is the major genetic risk factor for all stages of fatty liver disease, but the underlying p...
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Effects of a two meals-a-day ketogenic diet on newly diagnosed obese patients with type 2 diabetes mellitus: A retrospective observational study

To investigate the effects of a two-meals-a-day energy-restricted ketogenic diet (KD) on newly diagnosed obese patien...
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The Effect of Three Different Ketogenic Diet Protocols on Migraine and Fatigue in Chronic and High-Frequency Episodic Migraine: A Pilot Study

CONCLUSIONS: The VLCKD, LGID, and 2:1 KD may improve migraine intensity, frequency, and fatigue in chronic and high-f...
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Ketogenic Diet and Breast Cancer: Recent Findings and Therapeutic Approaches

Breast cancer (BC), a complex disease with several influencing factors, is significantly impacted by dietary habits. ...
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Ketone Bodies in Diabetes Mellitus: Friend or Foe?

In glucose-deprived conditions, ketone bodies are produced by the liver mitochondria, through the catabolism of fatty...
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The Impact of Nutritional Therapy in the Management of Overweight/Obese PCOS Patient Candidates for IVF

Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder, and it has two main pathological aspec...
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The ketone body β-hydroxybutyrate shifts microglial metabolism and suppresses amyloid-β oligomer-induced inflammation in human microglia

Fatty acids are metabolized by β-oxidation within the "mitochondrial ketogenic pathway" (MKP) to generate β-hydroxybu...
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Ketogenic diet may improve sleep quality and daytime somnolence in patients affected by multiple sclerosis. Results of an exploratory study

CONCLUSIONS: For the first time, we demonstrated that KD may improve sleep complaints in MS patients. In addition, KD...
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Diet and migraine: what is proven?

PURPOSE OF REVIEW: The purpose of this review is to present the latest research findings about diet and migraine, wha...
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Nutritional and metabolic control of germ cell fate through O-GlcNAc regulation

Fate determination of primordial germ cells (PGCs) is regulated in a multi-layered manner, involving signaling pathwa...
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Ketogenic Diet Affects Sleep Architecture in C57BL/6J Wild Type and Fragile X Mice

Nearly half of children with fragile X syndrome experience sleep problems including trouble falling asleep and freque...
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Ketogenic Diet and Multiple Health Outcomes: An Umbrella Review of Meta-Analysis

Numerous studies have examined the effects of ketogenic diets (KD) on health-related outcomes through meta-analyses. ...
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Weight Loss Promotion in Individuals with Obesity through Gut Microbiota Alterations with a Multiphase Modified Ketogenic Diet

The occurrence of obesity and related metabolic disorders is rising, necessitating effective long-term weight managem...
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Cancer Metabolism as a Therapeutic Target and Review of Interventions

Cancer is amenable to low-cost treatments, given that it has a significant metabolic component, which can be affected...
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The Present and Future of Optic Pathway Glioma Therapy

Optic pathway gliomas (OPGs) encompass two distinct categories: benign pediatric gliomas, which are characterized by ...
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MicroRNAs and Diet-induced Weight Loss: What's the Link?

It is now well established that lifestyle, particularly eating habits, modulates the synthesis and action of microRNA...
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Propofol for Anesthesia in Pediatric Patients With Epilepsy on the Ketogenic Diet: A Single-Center Experience

CONCLUSIONS: Boluses and brief infusions of propofol for anesthetic use in patients on the KD did not cause PIS in ou...
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Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants

CONCLUSION: Early treatment of IESS with efficient drugs is feasible in our country. Using standard protocols increas...
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Very-low-calorie ketogenic diet vs hypocaloric balanced diet in the prevention of high-frequency episodic migraine: the EMIKETO randomized, controlled trial

CONCLUSIONS: VLCKD is more effective than HBD in reducing MMD in patients with HFEM and represents an effective proph...
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The effect of a short-term ketogenic diet on exercise efficiency during graded exercise in healthy adults

CONCLUSIONS: Our data suggest that short-term KD is favorable to fat metabolism leading increased circulating FFA and...
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Persistent hypercalcemia mimicking hypophosphatasia after discontinuation of a ketogenic diet: a case report

CONCLUSIONS: Hypercalcemia may persist for an extended period after weaning from a KD; lab parameters may mimic that ...
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Glucose restriction induces AMPK-SIRT1-mediated circadian clock gene Per expression and delays NSCLC progression

The rhythmic expression of the circadian clock is intimately linked to the health status of the body. Disturbed circa...
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Editorial for "The Role of Ketogenic Diet in Human Health and Diseases": The Multifaceted Impact of Ketogenic Diets on Health and Disease

The ketogenic diet (KD), characterized by a very low carbohydrate intake and variable protein, fat and calorie intake...
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Can a modified ketogenic diet be a nutritional strategy for patients with McArdle disease? Results from a randomized, single-blind, placebo-controlled, cross-over study

CONCLUSION: The mKD did not alleviate all McArdle disease-related symptoms but did induce some positive changes. To d...
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Modified Atkins diet for drug-resistant epilepsy: A systematic review and meta-analysis of randomized controlled trials

OBJECTIVE: To evaluate the effectiveness and side-effect profile of the modified Atkins diet (MAD) compared to the us...
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Ketogenic diet and metastasis: A critical review of the literature and possible mechanisms

The ketogenic diet (KD) is a low-carb diet that has been indicated as a possible coadjuvant in cancer therapy, mainly...
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High-fat ketogenic diets and ketone monoester supplements differentially affect substrate metabolism during aerobic exercise

Chronically adhering to high-fat ketogenic diets or consuming ketone monoester supplements elicits ketosis. Resulting...
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The genetics of epilepsy in the clinical practice

Epilepsy is a neurological disorder characterized by recurrent unprovoked seizures. It is known that genetics play an...
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Adherence to ketogenic diet in lifestyle interventions in adults with overweight or obesity and type 2 diabetes: a scoping review

CONCLUSION: Our results demonstrated the need to develop intervention strategies to improve adherence to the KD, as w...
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Safe use of the ketogenic diet in an infant with microcephaly, epilepsy, and diabetes syndrome: a case report

CONCLUSIONS: We report two novel IER31P1 mutations in a patient with MEDS and the successful management of the cooccu...
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