Human Microbiome Research
"human microbiome"
"human microbiome": Latest results from PubMed
Early life gut microbiome and its impact on childhood health and chronic conditions
The development of the gut microbiome is crucial to human health, particularly during the first three years of life. ...
[more]
Antibiotic-associated changes in Akkermansia muciniphila alter its effects on host metabolic health
CONCLUSIONS: These findings highlight a previously unknown mechanism through which antibiotics influence host health ...
[more]
Characteristics of skin microbiome associated with disease severity in systemic sclerosis
Systemic sclerosis (SSc) is a chronic autoimmune disorder characterised by skin fibrosis and internal organ involveme...
[more]
Role of the Microbiome in Neonatal Infection: Pathogenesis and Implications for Management
The human microbiome refers to the collective genome of microorganisms, including bacteria, fungi, and viruses residi...
[more]
Coagulation Profile of Convalescent Plasma Donors and Recipients
Convalescent plasma (CP) therapy for COVID-19 infection may have favorable safety but varying efficacy, with concerns...
[more]
The COVID-19 vaccine ChAdOx1 is opsonized by anti-vector antibodies that activate complement and promote viral vector phagocytosis
The ChAdOx1 nCoV-19 vaccine has been in large-scale use during the COVID-19 pandemic. Limited efficacy compared to mR...
[more]
Interactions of human milk oligosaccharides with the immune system
Human milk oligosaccharides (HMOs) are abundant, diverse and complex sugars present in human breast milk. HMOs are we...
[more]
From Cure to Crisis: Understanding the Evolution of Antibiotic-Resistant Bacteria in Human Microbiota
The growing prevalence of antibiotic-resistant bacteria within the human microbiome has become a pressing global heal...
[more]
Metabolic profiles of meconium in preeclamptic and normotensive pregnancies
CONCLUSION: PE is associated with alterations in the meconium metabolome of infants. The differing abundances of seve...
[more]
Deep learning model targeting cancer surrounding tissues for accurate cancer diagnosis based on histopathological images
Accurate and fast histological diagnosis of cancers is crucial for successful treatment. The deep learning-based appr...
[more]
Longitudinal phage-bacteria dynamics in the early life gut microbiome
Microbial colonization of the human gut occurs soon after birth, proceeds through well-studied phases and is affected...
[more]
The Future of Microbiome Therapeutics
The human microbiome exerts profound influence over various biological processes within the body. Unlike many host de...
[more]
Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial
CONCLUSION: Overall, the administration of intravaginal estrogen and/or probiotics in pre-menopausal ACB women is fea...
[more]
Fermented foods affect the seasonal stability of gut bacteria in an Indian rural population
The effect of fermented foods on healthy human gut microbiota structure and function, particularly its seasonal prefe...
[more]
Association between the <em>ABCC11</em> gene polymorphism-determined earwax properties and external auditory canal microbiota in healthy adults
The concept of genome-microbiome interactions, in which the microenvironment determined by host genetic polymorphisms...
[more]
MultiTax-human: an extensive and high-resolution human-related full-length 16S rRNA reference database and taxonomy
Considering that the human microbiota plays a critical role in health and disease, an accurate and high-resolution ta...
[more]
Microproteins: emerging roles as antibiotics
Recent advances in computational prediction and experimental techniques have detected previously unknown microprotein...
[more]
Impact of simulation and reference catalogues on the evaluation of taxonomic profiling pipelines
Microbiome profiling tools rely on reference catalogues, which significantly affect their performance. Comparing them...
[more]
Spatio-Temporal Change of Skin and Oral Microbiota: A Longitudinal Study of Microbial Diversity and Stability
The human skin and oral cavity harbor complex microbial communities, which exist in dynamic equilibrium with the host...
[more]
Effects of Long-Term Fasting on Gut Microbiota, Serum Metabolome, and Their Association in Male Adults
CONCLUSIONS: Our pilot study suggests that alterations in gut microbiota during CF contribute to the shift of energy ...
[more]
Paleo Diet Research
paleo diet
paleo diet: Latest results from PubMed
High-resolution isotope dietary analysis of Mesolithic and Neolithic humans from Franchthi Cave, Greece
Franchthi Cave, in the Greek Peloponnese, is a well-known Paleolithic, Mesolithic and Neolithic site, with several hu...
[more]
Obesity and Weight Loss Diets in Inflammatory Bowel Disease Patients: What Physicians Should Know
Nutritional approach has been intensely investigated in inflammatory bowel disease (IBD) patients, but, despite many ...
[more]
Harnessing tumor metabolism during cancer treatment: A narrative review of emerging dietary approaches
Cancer is currently one of the biggest public health challenges worldwide, ranking as the second leading cause of dea...
[more]
Efficacy of a High-Protein Diet to Lower Glycemic Levels in Type 2 Diabetes Mellitus: A Systematic Review
Diabetes is a metabolic disease with a high worldwide prevalence and an important factor in mortality and disability ...
[more]
Trigger Warning: How Modern Diet, Lifestyle, and Environment Pull the Trigger on Autosomal Dominant Polycystic Kidney Disease Progression
Understanding chronic kidney disease (CKD) through the lens of evolutionary biology highlights the mismatch between o...
[more]
ALSUntangled #76: Wahls protocol
The Wahls diet is a modified Paleolithic diet that emphasizes dark green leafy vegetables, colorful fruits, high-qual...
[more]
Evaluating the effects of dietary patterns on circulating C-reactive protein levels in the general adult population: an umbrella review of meta-analyses of interventional and observational studies
Adopting a healthy dietary pattern may be an initial step in combating inflammation-related chronic diseases; however...
[more]
Dietary Recommendations for Glioma: A Mini-Review
PURPOSE OF REVIEW: Glioma is the most common type of brain cancer, associated with a high mortality rate. Diet is one...
[more]
Effects of a Paleolithic diet compared to a diabetes diet on leptin binding inhibition in secondary analysis of a randomised cross-over study
CONCLUSIONS: We found no leptin binding inhibition after the Paleolithic or diabetes diet, possibly due to its abolis...
[more]
Nutritional Management of Hashimoto's Thyroiditis: A Case Report
CONCLUSION: The Paleolithic diet may be used as a nutritional therapeutic protocol in those with HT with who have com...
[more]
From hunter-gatherers to food producers: New dental insights into the Nile Valley population history (Late Paleolithic-Neolithic)
OBJECTIVES: This study presents biological affinities between the last hunter-fisher-gatherers and first food-produci...
[more]
Insights into medieval rural lives: A paleo-odontological investigation of two central European communities
CONCLUSIONS: Using multiple dental parameters to examine the oral health of premodern individuals can provide useful ...
[more]
The Association Between Hidradenitis Suppurativa and Diet: An Update
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful inflammatory lesions,...
[more]
Spatial ecology of moose in Sweden: Combined Sr-O-C isotope analyses of bone and antler
The study of spatial (paleo)ecology in mammals is critical to understand how animals adapt to and exploit their envir...
[more]
The association between paleolithic diet pattern scores and psychological disorders in Iranian adults
CONCLUSIONS: Our research indicates that adhering to a Paleolithic diet, either alone or in conjunction with lifestyl...
[more]
Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review
Breast cancer (BC) is the most predominant malignancy in Arab women in the Middle East, and yearly increases in occur...
[more]
Multifunctional dietary interventions, low-grade inflammation and cardiometabolic profile: a scoping review
CONCLUSION: Our findings showed that multifunctional RCT diets have differential role in managing low-grade inflammat...
[more]
The effect of dietary interventions on inflammatory biomarkers among people with multiple sclerosis: A protocol for systematic review and meta-analysis of randomized controlled trials
BACKGROUND: Multiple sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system, characteriz...
[more]
Paleomicrobiology: Tracking the past microbial life from single species to entire microbial communities
By deciphering information encoded in degraded ancient DNA extracted from up to million-years-old samples, molecular ...
[more]
Impact of nutrition on the condition of the oral mucosa and periodontium: A narrative review
Diet and eating habits significantly affect health and quality of life. Various diets and food eliminations can lead ...
[more]
Ketogenic Diet Research
"ketogenic diet"
"ketogenic diet": Latest results from PubMed
Subacute Sclerosing Panencephalitis: Impact on Public Health, Current Insights, and Future Perspectives
CONCLUSION: The only prevention for SPPE is through vaccination. Several collaborative efforts have been made with WH...
[more]
Surgical Treatments, Devices, and Nonmedical Management of Epilepsy
OBJECTIVE: Many patients with epilepsy are unable to achieve optimal seizure control with medical therapy. This artic...
[more]
Early intrathecal dexamethasone (IT-Dexa) associated with faster recovery and good outcome in an adolescent with febrile infection-related epilepsy syndrome (FIRES)
A previously normal adolescent boy presented with a new-onset super refractory status epilepticus of unknown cause af...
[more]
Critical Review of Ketogenic Diet Throughout the Cancer Continuum for Neuroglioma: Insights from a Medical Nutrition Therapy (MNT) Perspective
PURPOSE OF REVIEW: A Ketogenic diet (KD; a diet comprised of 75% fat, 20% protein and 5% carbohydrates) has gained mu...
[more]
Ketogenic diet with oxyresveratrol and zinc inhibits glioblastoma and restores memory function and motor coordination
CONCLUSION: This study revealed the therapeutic effect of the ketogenic diet along with its combination such as oxyre...
[more]
The Role of Nutrition, Oxidative Stress, and Trace Elements in the Pathophysiology of Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficits in social communication an...
[more]
The Role of Lifestyle Interventions in PCOS Management: A Systematic Review
Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine disorders among reproductive-aged women. It i...
[more]
The Impact of a Very-Low-Calorie Ketogenic Diet on Monocyte Subsets of Patients with Obesity: A Pilot Study
Background/Objectives: Obesity is closely linked to chronic low-grade inflammation and the development of cardio-meta...
[more]
Supplementation with essential amino acids in the early stage of carbohydrate reintroduction after a very-low energy ketogenic therapy (VLEKT) improves body cell mass, muscle strength and inflammation
CONCLUSION: These results underline the usefulness of supplementation with EAAs during the first transitional phase p...
[more]
Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice
The gut microbiome modulates the anti-seizure effects of the ketogenic diet, but how specific dietary formulations di...
[more]
Pilot study of a ketogenic diet in bipolar disorder: a process evaluation
CONCLUSION: We provide novel insight into the experiences of people living with bipolar disorder initiating and follo...
[more]
A Very Low-Carbohydrate Program in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease and Phospholipase Domain-Containing Protein 3 Risk Genotype: Pre-Post Intervention Study
CONCLUSIONS: Results suggest the feasibility, acceptability, and preliminary efficacy of the VLC intervention in adul...
[more]
Dietary Influences on Gut Microbiota and Their Role in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major contributor to liver-related morbidity, c...
[more]
Therapeutic Potential of Ketogenic Interventions for Autosomal-Dominant Polycystic Kidney Disease: A Systematic Review
CONCLUSIONS: Human studies are promising; however, they have been limited by small sample sizes and short durations. ...
[more]
Ketogenic Diet as a Nutritional Metabolic Intervention for Obsessive-Compulsive Disorder: A Narrative Review
The substantial evidence supporting the ketogenic diet (KD) in epilepsy management has spurred research into its effe...
[more]
Hepatic metabolism and ketone production in metabolic dysfunction-associated steatotic liver disease
PURPOSE OF REVIEW: Metabolic dysfunction-associated steatotic liver disease (MASLD) is present in 25-35% of individua...
[more]
Application and Mechanism of Action of a Ketogenic Diet in Antiepileptic Therapy
Epilepsy is a chronic neurological disorder caused by abnormal discharges of neurons in the brain, which seriously af...
[more]
Exploring the potential of gemcitabine-metal-organic frameworks in combating pancreatic cancer under ketogenic conditions
CONCLUSION: The use of metal-organic framework to encapsulate gemcitabine yielded notable pro-apoptotic effects in MI...
[more]
The Long-Term Treatment of Drug-Resistant Migraine with the Modified Atkins Ketogenic Diet: A Single-Center, Retrospective Study
Despite advances in pharmacological therapies, migraine patients are often drug resistant. Further therapeutic option...
[more]
Effects of the Ketogenic Diet on Microbiota Composition and Short-Chain Fatty Acids in Women with Overweight/Obesity
Background/Objectives: The ketogenic diet (KD) is a dietary model that can impact metabolic health and microbiota and...
[more]
Development and Pragmatic Randomized Controlled Trial of Healthy Ketogenic Diet Versus Energy-Restricted Diet on Weight Loss in Adults with Obesity
Introduction: The ketogenic diet (KD) is widely used for weight management by reducing appetite, enhancing fat oxidat...
[more]
Exploring the potential of the ketogenic diet in autism spectrum disorder: metabolic, genetic, and therapeutic insights
Current treatment approaches for Autism spectrum disorder (ASD) primarily focus on symptom management rather than add...
[more]
Micronutrients intake in patients with refractory epilepsy with ketogenic diet treatment
CONCLUSIONS: The micronutrient intake in the different KD modalities is low for most of them, being the MAD with form...
[more]
Long-Term Efficacy and Safety of Nutritional and Pharmacological Strategies for Obesity
PURPOSE OF REVIEW: This review examines the long-term efficacy and safety of various nutritional and pharmacological ...
[more]
Promising therapeutic strategies for Lennox-Gastaut syndrome: what's new?
INTRODUCTION: The seizures in Lennox-Gastaut syndrome are typically resistant to treatment. Seven antiseizure medicat...
[more]
Refining management strategies for Lennox-Gastaut syndrome: Updated algorithms and practical approaches
Lennox-Gastaut syndrome (LGS) is a severe developmental and epileptic encephalopathy (DEE) characterized by multiple ...
[more]
KETO-MOOD: Ketogenic Diet for Microbiome Optimization and Overcoming Depression - A Protocol for a Randomized Controlled Trial
CONCLUSION: This study addresses a critical gap in depression treatment by exploring the ketogenic diet's potential a...
[more]
Ketogenic diet as a therapeutic approach in autism spectrum disorder: a narrative review
The ketogenic diet (KD) originated in the 1920s. It is a dietary model that is low in carbohydrates, adequate in prot...
[more]
Ketogenic Diet and Neuroinflammation: Implications for Neuroimmunometabolism and Therapeutic Approaches to Refractory Epilepsy
Refractory epilepsy, characterized by seizures that do not respond to standard antiseizure medications, remains a sig...
[more]
Does the Ketogenic Diet Mediate Inflammation Markers in Obese and Overweight Adults? A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Background/Objectives. The ketogenic diet has emerged as a potential treatment strategy for reducing inflammation. Th...
[more]
The Effectiveness of the Low-Glycemic and Insulinemic (LOGI) Regimen in Maintaining the Benefits of the VLCKD in Fibromyalgia Patients
Background: Fibromyalgia (FM) is a chronic disorder that causes damage to the neuro-muscular system and alterations i...
[more]
An 8-Week Very Low-Calorie Ketogenic Diet (VLCKD) Alters the Landscape of Obese-Derived Small Extracellular Vesicles (sEVs), Redefining Hepatic Cell Phenotypes
Background. Very low-calorie ketogenic diets (VLCKD) are an effective weight-loss strategy for obese individuals, red...
[more]
The Cardioprotective Effects of Nutritional Ketosis: Mechanisms and Clinical Implications
Cardiovascular diseases (CVDs) persist as the primary cause of death worldwide, accounting for roughly 17.9 million f...
[more]
Effects of a 12 Week Ketogenic Diet Intervention on Obese and Overweight Females with Glucose and Lipid Metabolism Disturbance
CONCLUSIONS: A 12-week KD led to more pronounced improvements in biochemical markers and body mass in obese females c...
[more]
Chapters from alcohology
A más módon nem kezelhető epilepsziás betegek terápiájára a múlt század első felében bevezetett ketogén diéta ma már ...
[more]
Diet as an Adjunct Therapy in Reducing Chemotherapy Toxicities and Improving Patients Quality of Life: A Systematic Review and Meta-Analysis
This review analyzed existing literature regarding the relationship between different diets and chemotherapy toxiciti...
[more]
Impact of short-term ketogenic diet on sex hormones and glucose-lipid metabolism in overweight or obese patients with polycystic ovary syndrome
CONCLUSION: The short-term KD treatment provides significant weight loss and effectively improves hormone regulation ...
[more]
Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal
Glucose transporter type 1 deficiency syndrome (GLUT1DS) commonly presents with early-onset epilepsy that often resis...
[more]
Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally lethal prognosis despite ...
[more]
Current situation and challenge of exogenous 3-hydroxybutyrate derived from polyhydroxyalkanoates for elderly health: A review
3-Hydroxybutyrate (3HB), predominantly found in the liver, muscles, and brain, is the most important endogenous keton...
[more]
The effects of portfolio moderate-carbohydrate and ketogenic diets on anthropometric indices, metabolic status, and hormonal levels in overweight or obese women with polycystic ovary syndrome: a randomized controlled trial
CONCLUSION: The findings revealed that both diets were effective in improving PCOS manifestations. However, the KD ex...
[more]
Integrating alternative and complementary medicine in the management of epilepsy and its comorbidities in low- and middle-income settings
Traditional/alternative and complementary medicine (TCM) encompasses products, practices and practitioners that do no...
[more]
β-hydroxybutyrate suppresses pathological changes of blood-induced arthropathy in rats
Arthropathy is a common complication in haemophilia and decreases quality of life. It has been known that concentrati...
[more]
Evaluation of uric acid levels and other biochemical parameters among Gout patients with Ketogenic diet in Erbil province
Gout is a systemic disorder that occurs due to an accumulation of uric acid crystals in the tissues. The association ...
[more]
Safety and Effectiveness of a 4-Week Diet on Low-Carb Ready-to-Eat Ketogenic Products as Preoperative Care Treatment in Patients Scheduled for Metabolic and Bariatric Surgery
Before metabolic and bariatric surgery (MBS), moderate weight loss and liver left lateral section (LLLS) volume reduc...
[more]
Low-Dose Ketone Monoester Administration in Adults with Cystic Fibrosis: A Pilot and Feasibility Study
CONCLUSIONS: With the emerging role of exogenous ketones as nutrient signaling molecules and mediators of metabolism,...
[more]
Ketogenic diet in adult patients with mitochondrial myopathy
BACKGROUND: This study aimed to explore the feasibility, safety and efficacy of a Modified Atkins Diet (MAD) in patie...
[more]
Measuring the effects of ketogenic diet on neuropsychiatric disorder: A scoping review
CONCLUSION: The KD may serve as a promising therapeutic intervention for various neuropsychiatric disorders. However,...
[more]
Harnessing tumor metabolism during cancer treatment: A narrative review of emerging dietary approaches
Cancer is currently one of the biggest public health challenges worldwide, ranking as the second leading cause of dea...
[more]
The LDL Receptor-Related Protein 1: Mechanisms and roles in promoting Aβ efflux transporter in Alzheimer's disease
The LDL Receptor-Related Protein 1(LRP1), a member of the Low-density Lipoprotein (LDL) receptor family, is a multifu...
[more]