Human Microbiome Research
"human microbiome"
"human microbiome": Latest results from PubMed
Tip extension and simultaneous multiple fission in a filamentous bacterium
Organisms display an immense variety of shapes, sizes, and reproductive strategies. At microscopic scales, bacterial ...
[more]
Bacterial association with metals enables in vivo monitoring of urogenital microbiota using magnetic resonance imaging
Bacteria constitute a significant part of the biomass of the human microbiota, but their interactions are complex and...
[more]
Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA study
CONCLUSION: This exploratory study shows that prebiotic consumption by lactating mothers selectively alters specific ...
[more]
Radiogenomic profiling of global DNA methylation associated with molecular phenotypes and immune features in glioma
CONCLUSIONS: Global DNA methylation is highly associated with radiological profiles in glioma. Radiogenomic global me...
[more]
Targeted isolation of Methanobrevibacter strains from fecal samples expands the cultivated human archaeome
Archaea are vital components of the human microbiome, yet their study within the gastrointestinal tract (GIT) is limi...
[more]
Different Prostatic Tissue Microbiomes between High- and Low-Grade Prostate Cancer Pathogenesis
Numerous human pathologies, such as neoplasia, are related to particular bacteria and changes in microbiome constitue...
[more]
Fecal microbiota transplantation influences microbiota without connection to symptom relief in irritable bowel syndrome patients
Imbalanced microbiota may contribute to the pathophysiology of irritable bowel syndrome (IBS), thus fecal microbiota ...
[more]
The assembly of neutrophil inflammasomes during COVID-19 is mediated by type I interferons
The severity of COVID-19 is linked to excessive inflammation. Neutrophils represent a critical arm of the innate immu...
[more]
Mechanism of probiotics in the intervention of colorectal cancer: a review
The human microbiome interacts with the host mainly in the intestinal lumen, where putrefactive bacteria are suggeste...
[more]
Microbial assimilatory sulfate reduction-mediated H<sub>2</sub>S: an overlooked role in Crohn's disease development
CONCLUSIONS: Our study significantly advances understanding of microbial sulfur metabolism in the human gut, elucidat...
[more]
Unlocking the mind-gut connection: Impact of human microbiome on cognition
This perspective explores the current understanding of the gut microbiota's impact on cognitive function in apparentl...
[more]
Identification of microbe-disease signed associations via multi-scale variational graph autoencoder based on signed message propagation
CONCLUSIONS: MSignVGAE achieves AUROC and AUPR values of 0.9742 and 0.9601, respectively. Case studies on three disea...
[more]
Associations between gut microbiota and incident fractures in the FINRISK cohort
The gut microbiota (GM) can regulate bone mass, but its association with incident fractures is unknown. We used Cox r...
[more]
Skin Aging and the Upcoming Role of Ferroptosis in Geroscience
The skin is considered the most important organ system in mammals, and as the population ages, it is important to con...
[more]
'Tiny Biome Tales': A gamified review about the influence of lifestyle choices on the human microbiome
In the last two decades, new discoveries from microbiome research have changed our understanding of human health. It ...
[more]
Induction of Cell Death by <em>Bifidobacterium infantis</em> DS1685 in Colorectal and Breast Cancers via SMAD4/TGF-Beta Activation
Therapeutic advancements in treatments for cancer, a leading cause of mortality worldwide, have lagged behind the inc...
[more]
The Human Microbiome-A Physiologic Perspective
The human microbiome consists of the microorganisms associated with the body, such as bacteria, fungi, archaea, proto...
[more]
DeepMineLys: Deep mining of phage lysins from human microbiome
Vast shotgun metagenomics data remain an underutilized resource for novel enzymes. Artificial intelligence (AI) has i...
[more]
Mouse adaptation of human inflammatory bowel diseases microbiota enhances colonization efficiency and alters microbiome aggressiveness depending on the recipient colonic inflammatory environment
CONCLUSIONS: Our findings support a model of IBD pathogenesis in which host inflammation promotes aggressive resident...
[more]
Improvement of a mouse infection model to capture <em>Pseudomonas aeruginosa</em> chronic physiology in cystic fibrosis
Laboratory models are central to microbiology research, advancing the understanding of bacterial physiology by mimick...
[more]
Paleo Diet Research
paleo diet
paleo diet: Latest results from PubMed
Nutritional Management of Hashimoto's Thyroiditis: A Case Report
CONCLUSION: The Paleolithic diet may be used as a nutritional therapeutic protocol in those with HT with who have com...
[more]
From hunter-gatherers to food producers: New dental insights into the Nile Valley population history (Late Paleolithic-Neolithic)
OBJECTIVES: This study presents biological affinities between the last hunter-fisher-gatherers and first food-produci...
[more]
Insights into medieval rural lives: A paleo-odontological investigation of two central European communities
CONCLUSIONS: Using multiple dental parameters to examine the oral health of premodern individuals can provide useful ...
[more]
The Association Between Hidradenitis Suppurativa and Diet: An Update
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful inflammatory lesions,...
[more]
Spatial ecology of moose in Sweden: Combined Sr-O-C isotope analyses of bone and antler
The study of spatial (paleo)ecology in mammals is critical to understand how animals adapt to and exploit their envir...
[more]
Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review
Breast cancer (BC) is the most predominant malignancy in Arab women in the Middle East, and yearly increases in occur...
[more]
Multifunctional dietary interventions, low-grade inflammation and cardiometabolic profile: a scoping review
CONCLUSION: Our findings showed that multifunctional RCT diets have differential role in managing low-grade inflammat...
[more]
The effect of dietary interventions on inflammatory biomarkers among people with multiple sclerosis: A protocol for systematic review and meta-analysis of randomized controlled trials
BACKGROUND: Multiple sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system, characteriz...
[more]
Paleomicrobiology: Tracking the past microbial life from single species to entire microbial communities
By deciphering information encoded in degraded ancient DNA extracted from up to million-years-old samples, molecular ...
[more]
Impact of nutrition on the condition of the oral mucosa and periodontium: A narrative review
Diet and eating habits significantly affect health and quality of life. Various diets and food eliminations can lead ...
[more]
Inverse association between Paleolithic Diet Fraction and mortality and incidence of cardiometabolic disease in the prospective Malmo Diet and Cancer Study
CONCLUSION: Observational data suggest an inverse association between PDF and all-cause as well as cause-specific mor...
[more]
Adherence to Healthy Dietary Patterns and Glioma: A Matched Case-Control Study
Recent studies have revealed a putative relationship between diet and glioma development and prognosis, but few studi...
[more]
The value of ethnographic studies for making inferences about the nature of the human Paleolithic diet: comments on Lieberman et al. (2023)
No abstract
[more]
Popular Diets and Skin Effects: A Narrative Review
Numerous diets for losing weight, building strength, and managing a range of cardiovascular, neurologic, and skin dis...
[more]
Impact of Paleo Diet on Body Composition, Carbohydrate and Fat Metabolism of Professional Handball Players
The Paleo diet (PD) involves a restriction of carbohydrates and increased fat content (35% energy from carbohydrates,...
[more]
Adherence to the Paleolithic diet and Paleolithic-like lifestyle reduce the risk of colorectal cancer in the United States: a prospective cohort study
CONCLUSIONS: Our findings suggest that adhering to the PD and PLL could be a new option to reduce CRC risk.
[more]
Hunter-gatherer diets and activity as a model for health promotion: Challenges, responses, and confirmations
Beginning in 1985, we and others presented estimates of hunter-gatherer (and ultimately ancestral) diet and physical ...
[more]
Evaluation of a web-based program for the adoption of wellness behaviors to self-manage fatigue and improve quality of life among people with multiple sclerosis: A randomized waitlist-control trial
CONCLUSION: A wellness intervention delivered via a web-based program, without tailored support, resulted in signific...
[more]
Comparing measured dietary variation within and between tropical hunter-gatherer groups to the Paleo Diet
CONCLUSIONS: The ethnographic evidence from tropical foragers refutes the concept of circumscribed macronutrient rang...
[more]
Association of serum homocysteine, folate, and vitamin B<sub>12</sub> and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial
CONCLUSION: Participants on both Swank and Wahls dietary interventions, including folate and vitamin B(12) supplement...
[more]
Ketogenic Diet Research
"ketogenic diet"
"ketogenic diet": Latest results from PubMed
Potential Add-On Benefits of Dietary Intervention in the Treatment of Autosomal Dominant Polycystic Kidney Disease
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of renal failure. The pathoge...
[more]
Ketogenic Interventions in Autosomal Dominant Polycystic Kidney Disease: A Comprehensive Review of Current Evidence
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder characterized by the development and enlar...
[more]
Exploring the ketogenic diet's potential in reducing neuroinflammation and modulating immune responses
The ketogenic diet (KD) is marked by a substantial decrease in carbohydrate intake and an elevated consumption of fat...
[more]
Enhancing understanding of dietary interventions in obesity: Insights and recommendations for future research
No abstract
[more]
Angelman syndrome in Poland: current diagnosis and therapy status-the caregiver perspective: a questionnaire study
CONCLUSIONS: The care of patients with AS in Poland is carried out according to the European and world standards, how...
[more]
Self-reported menses physiology is positively modulated by a well-formulated, energy-controlled ketogenic diet vs. low fat diet in women of reproductive age with overweight/obesity
Weight loss can positively alter female physiology; however, whether dietary carbohydrate- or fat- restriction confer...
[more]
The basics of metabolic psychiatry
The stability of brain functions is mainly determined by the energy management of the cells, and mental health is, th...
[more]
<em>MED23</em> pathogenic variant: genomic-phenotypic analysis
The mediator complex subunit 23 (MED23) gene encodes a protein that acts as a tail module mediator complex, a multi-s...
[more]
Dietary Pattern and Cancer
Diet play an important role in the development of cancer. A lot of research has been done on the role of individual n...
[more]
Ketogenic diet reshapes cancer metabolism through lysine beta-hydroxybutyrylation
Lysine β-hydroxybutyrylation (Kbhb) is a post-translational modification induced by the ketogenic diet (KD), a diet s...
[more]
Influence of Carbohydrate Intake on Caprylic Acid (C8:0)-Induced Ketogenesis-A Systematic Review and Meta-Analysis
The ketogenic diet is used worldwide to treat various diseases, especially drug-resistant epilepsies. Medium-chain tr...
[more]
Metabolic Insights into Neuropsychiatric Illnesses and Ketogenic Therapies: A Transcriptomic View
The disruption of brain energy metabolism, leading to alterations in synaptic signaling, neural circuitry, and neurop...
[more]
Extracellular Vesicles Modulate Liver Cells Viability and Reactive Oxygen Species in Patients Following a Very Low-Calorie Ketogenic Diet
The VLCKD is a diet recognized to promote rapid fat mobilization and reduce inflammation, hepatic steatosis, and live...
[more]
Ketogenic diet but not free-sugar restriction alters glucose tolerance, lipid metabolism, peripheral tissue phenotype, and gut microbiome: RCT
Restricted sugar and ketogenic diets can alter energy balance/metabolism, but decreased energy intake may be compensa...
[more]
Impact of the ketogenic diet as a dietary approach on cardiovascular disease risk factors: a meta-analysis of randomized clinical trials
CONCLUSIONS: Although the ketogenic diet demonstrates benefits in terms of triglyceride, blood pressure, weight, and ...
[more]
Targeting fatty acid oxidation enhances response to HER2-targeted therapy
Metabolic reprogramming, a hallmark of tumorigenesis, involves alterations in glucose and fatty acid metabolism. Here...
[more]
Efficacy of anti-seizure medications and alternative therapies (ketogenic diet, CBD, and quinidine) in KCNT1-related epilepsy: A systematic review
OBJECTIVE: KCNT1-related epilepsies encompass three main phenotypes: (i) epilepsy of infancy with migrating focal sei...
[more]
Relationship of Ketosis With Myocardial Glucose Uptake Among Patients Undergoing FDG PET/CT for Evaluation of Cardiac Sarcoidosis
CONCLUSIONS: We observed a strong inverse relationship between ketosis and patterns of MGU. Longer KD and fasting dur...
[more]
PURA-Related Neurodevelopmental Disorders with Epilepsy Treated with Ketogenic Diet: A Case-Based Review
PURA syndrome is a congenital developmental disorder caused by de novo mutations in the PURA gene, which encodes a DN...
[more]
Effects of the Ketogenic Diet on Strength Performance in Trained Men and Women: A Systematic Review and Meta-Analysis
Ketogenic diets (KDs) are an alternative to improve strength performance and body composition in resistance training ...
[more]
Advances in Diet and Physical Activity in Breast Cancer Prevention and Treatment
There is currently a growing interest in diets and physical activity patterns that may be beneficial in preventing an...
[more]
Neurodevelopment Is Dependent on Maternal Diet: Placenta and Brain Glucose Transporters GLUT1 and GLUT3
Glucose is the primary energy source for most mammalian cells and its transport is affected by a family of facilitati...
[more]
Current advances in cancer energy metabolism under dietary restriction: a mini review
The manipulation of the energy or source of food for cancer cells has attracted significant attention in oncology res...
[more]
The reality of epilepsy in primary care in Rio de Janeiro: the importance of educational projects for better patient care
CONCLUSION: There are deficits in the knowledge of UBS professionals in the management of epilepsy. Specialized trai...
[more]
A New Nomenclature for the Very Low-Calorie Ketogenic Diet (VLCKD): Very Low-Energy Ketogenic Therapy (VLEKT). Ketodiets and Nutraceuticals Expert Panels: "KetoNut", Italian Society of Nutraceuticals (SINut) and the Italian Association of Dietetics and Clinical Nutrition (ADI)
PURPOSE OF REVIEW: In an attempt to clarify the most appropriate nomenclature for the very low-calorie ketogenic diet...
[more]
Ketogenic diet therapy leads to antiseizure medication reduction in children and adults with drug-resistant epilepsy
CONCLUSION: This study demonstrates the safe achievability of ASM withdrawal through KDT in most patients with DRE, i...
[more]
Very Low Calorie Ketogenic Diet: What Effects on Lipid Metabolism?
PURPOSE OF REVIEW: This review aims to critically examine how VLCKD affects plasma lipoprotein, lipid and cholesterol...
[more]
Intermittent fasting, calorie restriction, and a ketogenic diet improve mitochondrial function by reducing lipopolysaccharide signaling in monocytes during obesity: A randomized clinical trial
CONCLUSIONS: We conclude that these dietary interventions positively regulate mitochondrial bioenergetic health and i...
[more]
Evaluation of seizure semiology, genetics, magnetic resonance imaging, and electroencephalogram findings in children with Rett syndrome: A multicenter retrospective study
CONCLUSION: This study underscores the importance of genetic diagnosis in RTT cases with a clinical diagnosis. These ...
[more]
Effects of a Ketogenic Diet on Body Composition in Healthy, Young, Normal-Weight Women: A Randomized Controlled Feeding Trial
This study investigates the effects of a ketogenic low-carbohydrate high-fat (LCHF) diet on body composition in healt...
[more]
A Multi-Omics Approach to Disclose Metabolic Pathways Impacting Intestinal Permeability in Obese Patients Undergoing Very Low Calorie Ketogenic Diet
A very low calorie ketogenic diet (VLCKD) impacts host metabolism in people marked by an excess of visceral adiposity...
[more]
Metabolic Effects of Ketogenic Diets: Exploring Whole-Body Metabolism in Connection with Adipose Tissue and Other Metabolic Organs
The ketogenic diet (KD) is characterized by minimal carbohydrate, moderate protein, and high fat intake, leading to k...
[more]
Positive and negative schizotypy personality traits are lower in individuals on ketogenic diet in a non-clinical sample
Schizotypal personality comprises traits such as odd beliefs, perceptual abnormalities, and social difficulties; thes...
[more]
Ketogenic diet improves chromatin remodeling and rescues mitochondrial dysfunction in ischemic heart disease by regulating PGC-1alpha transcription
No abstract
[more]
An open-label, randomized controlled trial to assess a ketogenic diet in critically ill patients with sepsis
Patients with sepsis experience metabolic and immunologic dysfunction that may be amplified by standard carbohydrate-...
[more]
Letter to the Editor: Ketogenic diet time-dependently prevents nonalcoholic fatty liver disease through upregulating the expression of antioxidant protein metallothionein-2
No abstract
[more]
Anticancer restrictive diets and the risk of psychological distress: Review and perspectives
CONCLUSIONS AND PERSPECTIVES: In the absence of a conclusive evidence on the clinical benefits of restrictive diets, ...
[more]
Unraveling unmet needs in ketogenic dietary services: An ERN EpiCARE survey
The implementation and potential of ketogenic dietary therapies (KDTs) have changed over time. The organization of KD...
[more]
The diagnostic and prognostic role of cerebrospinal fluid biomarkers in glucose transporter 1 deficiency: a systematic review
The purpose of this study is to investigate the diagnostic and prognostic role of cerebrospinal fluid (CSF) biomarker...
[more]
Advances in Ketogenic Diet Therapies in Pediatric Epilepsy: A Systematic Review
Objective: To review the effects of the ketogenic diet on epilepsy in children and adolescents.
[more]
Effects of ketogenic diet on cognitive function of patients with Alzheimer's disease: a systematic review and meta-analysis
CONCLUSION: Research conducted has indicated that the KD can enhance the mental state and cognitive function of those...
[more]
Mediterranean ketogenic diet accounts for reduced pain frequency and intensity in patients with chronic migraine: A pilot study
CONCLUSION: Overall, Mediterranean-ketogenic diet may be considered an effective non-pharmacological intervention for...
[more]
The Assessment of the Efficacy, Safety, and Challenges of Ketogenic Diet Therapy in Children with Epilepsy: The First Experience of a Single Center
Background and Objectives: Ketogenic diet therapy (KDT) has been used as a non-pharmacological treatment for childhoo...
[more]
Long-Term Fasting-Induced Ketosis in 1610 Subjects: Metabolic Regulation and Safety
CONCLUSION: Our study showed that long-term fasting triggered ketosis, never reaching pathological levels, and that k...
[more]
International society of sports nutrition position stand: ketogenic diets
POSITION STATEMENT: The International Society of Sports Nutrition (ISSN) provides an objective and critical review of...
[more]
Ketogenic diet-induced bile acids protect against obesity through reduced calorie absorption
The low-carbohydrate ketogenic diet (KD) has long been practiced for weight loss, but the underlying mechanisms remai...
[more]
Effects of ketogenic diets on cancer-related variables: A systematic review and meta-analysis of randomised controlled trials
Cancer is a global health concern influenced by genetics, environment and lifestyle choices. Recent research shows th...
[more]