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Food For Thought

Food for Thought MicrobiomeHuman Microbiome Research

"human microbiome"

"human microbiome": Latest results from PubMed

Pre-digestion of soybeans, fermentation with fructophilic lactic acid bacteria, and in silico analyses to uncover psychobiotic potential

Psychobiotics are emerging as key players in gut-brain axis research, yet the role of Fructophilic Lactic Acid Bacter...
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Shotgun metagenomics reveals distinct skin microbial species in allergen-sensitized individuals

The Karelian region, which spans the border between Finland and Russia, presents distinct environmental exposures and...
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Impact of data compositionality on the detection of microbiota responses

Next-generation sequencing (NGS) data usage is widespread, but its compositional nature poses challenges. We evaluate...
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STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies

The interdisciplinary nature of microbiome research, coupled with the generation of complex multi-omics data, makes k...
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MicroMap: a network visualisation resource for human microbiome metabolism

The human microbiome critically influences metabolism and thereby our health. Constraint-based reconstruction and ana...
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The Human Archaeome: Commensals, Opportunists, or Emerging Pathogens?

Archaea, one of the three domains of life, are increasingly recognized as consistent, though often underappreciated, ...
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Joint Bacterial Traces in the Gut and Oral Cavity of Obesity Patients Provide Evidence for Saliva as a Rich Microbial Biomarker Source

Background: The human microbiome holds promise for identifying biomarkers and therapeutic targets. In obesity, intera...
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Laser-assisted microbial culturomics

Even though metagenomics have revolutionized the characterization of the human microbiome, detailed mechanistic studi...
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Calculating fast differential genome coverages among metagenomic sources using micov

Breadth of coverage, the proportion of a reference genome covered by at least one sequencing read, is critical for in...
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Serum metabolites link immune-microbiota interaction in children and young adults from Russian Karelia and Finnish Karelia with contrasting lifestyle and environment

CONCLUSIONS: Multi-omics integration revealed a more coordinated and responsive immune-metabolic network in RUS youth...
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Mutanobactin D from the Human Microbiome: Chemistry, Biology, and Molecular Dynamics Studies

Mutanobactin D is an interkingdom communicator derived from the human oral microbiome. The lipopeptide prevents yeast...
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The hidden players: The mycobiome of pancreatic ductal adenocarcinoma tumors

The microorganisms that inhabit the human body are known to play a role in human health and disease. Continuing to el...
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Two of a kind, one with MS: Gut microbes tip the balance

An MS twin study links ileal Lachnospiraceae to spontaneous CNS autoimmunity in mice receiving a human microbiome tra...
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Predicting age from binarized human oral microbial data combined with an ensemble of classifiers

It is well established that the composition of the human microbiome changes with age; however, limited research has e...
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Microbiome and well-being: a meta-analysis

The human microbiome may play a significant role in both health and disease. However, most studies to date have focus...
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Peculiarities of vaginal microbiota in perimenopausal and postmenopausal women with type 2 diabetes mellitus

CONCLUSION: Under perimenopausal and postmenopausal conditions, T2DM disrupts vaginal microbiota homeostasis by dimin...
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The role of gut mycobiome in responses to cancer immunotherapy

The gut microbiome has emerged as an important modulator of cancer progression and therapy response, yet the role of ...
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Sparse Canonical Correlation Analysis for Multiple Measurements With Latent Trajectories

Canonical correlation analysis (CCA) is a widely used multivariate method in omics research for integrating high-dime...
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Host-specific bacterial modulation of airway gene expression and alternative splicing

The human microbiome varies extensively between individuals. While there are numerous studies investigating the effec...
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Mammary Gland Microbiota in Benign Breast Diseases

The human microbiome is a critical factor in health and disease. While its association with breast cancer (BC) has be...
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Food for Thought Paleo Diet 2Paleo Diet Research

paleo diet

paleo diet: Latest results from PubMed

Association between Paleolithic diet fraction and systemic low-grade chronic inflammation in the Malmo diet and cancer study cohort

CONCLUSION: PDF was inversely associated with SLGCI biomarkers, suggesting that SLGCI may mediate its relationship wi...
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Efficacy of Diet on Quality of life in Multiple Sclerosis (EDQ-MS): a study protocol for a randomized controlled clinical trial

BACKGROUND: The primary objective of this study is to evaluate the efficacy of two dietary interventions, time-restri...
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Archaeological Research on Dental Caries

Dental caries, a chronic infectious disease affecting oral health, has undergone significant evolution in its epidemi...
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Nutrition and pregnancy : pragmatic recommendations

Pregnancy entails specific nutritional needs, yet dietary recommendations are often perceived as overly restrictive. ...
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Examination of social media nutrition information related to multiple sclerosis: a cross-sectional social network analysis

CONCLUSIONS: Nutrition misinformation for MS occurs on social media and information quality is variable. Audiences ne...
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Randomised crossover controlled trial of dietary interventions for glycaemic control when body weight is kept stable

A Palaeolithic diet is an efficacious dietary approach for glycaemic control in type 2 diabetes. Causal mechanisms ar...
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Untangling the role of diet quality and other risk factors in the severity of metabolic syndrome: Insights from the Hoveyzeh Cohort study using structural equation modeling

CONCLUSION: The findings emphasize that improving diet quality as a means of managing modifiable risk factors may red...
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Large-scale processing of within-bone nutrients by Neanderthals, 125,000 years ago

Diet played a key role in human evolution, making the study of past diet and subsistence strategies a crucial researc...
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Perceptions of the effects of following specific diets among people with multiple sclerosis: A web scraping analysis of the multiple sclerosis subreddit

CONCLUSION: Users of the r/MultipleSclerosis subreddit increasingly discussed diets over a 12.5-year period and repor...
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Scoring adherence to voluntary restriction diets (SAVoReD) in the ADAPT study

Voluntary adoption of popular food-group-restricting diets like Paleo and plant-based diets (PBDs) are often health-m...
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Assessing Breastfeeding Attitudes and Self-Efficacy Among Health care Personnel and Women With Multiple Sclerosis: Two Cross-Sectional Surveys

INTRODUCTION: This study aimed to describe breastfeeding attitudes among health care personnel, as well as breastfeed...
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Effects of a Multimodal Lifestyle Intervention on Cardiometabolic Markers in People with Progressive Multiple Sclerosis: A Secondary Analysis of a Pilot Study

Background: Cardiometabolic comorbidities are common in multiple sclerosis (MS), and lifestyle interventions are effe...
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High-resolution isotope dietary analysis of Mesolithic and Neolithic humans from Franchthi Cave, Greece

Franchthi Cave, in the Greek Peloponnese, is a well-known Paleolithic, Mesolithic and Neolithic site, with several hu...
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Obesity and Weight Loss Diets in Inflammatory Bowel Disease Patients: What Physicians Should Know

Nutritional approach has been intensely investigated in inflammatory bowel disease (IBD) patients, but, despite many ...
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Harnessing tumor metabolism during cancer treatment: A narrative review of emerging dietary approaches

Cancer is currently one of the biggest public health challenges worldwide, ranking as the second leading cause of dea...
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Efficacy of a High-Protein Diet to Lower Glycemic Levels in Type 2 Diabetes Mellitus: A Systematic Review

Diabetes is a metabolic disease with a high worldwide prevalence and an important factor in mortality and disability ...
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Trigger Warning: How Modern Diet, Lifestyle, and Environment Pull the Trigger on Autosomal Dominant Polycystic Kidney Disease Progression

Understanding chronic kidney disease (CKD) through the lens of evolutionary biology highlights the mismatch between o...
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ALSUntangled #76: Wahls protocol

The Wahls diet is a modified Paleolithic diet that emphasizes dark green leafy vegetables, colorful fruits, high-qual...
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Dietary Recommendations for Glioma: A Mini-Review

PURPOSE OF REVIEW: Glioma is the most common type of brain cancer, associated with a high mortality rate. Diet is one...
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ButterKetogenic Diet Research

"ketogenic diet"

"ketogenic diet": Latest results from PubMed

Ketogenic diet therapy in adolescents and adults with drug resistant epilepsy. Experience in Uruguay

INTRODUCTION: Ketogenic diet therapies constitute an option for drug resistant epilepsies and have been mostly used i...
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Effect of ketogenic diet plus dulaglutide on glucose and lipid metabolism in diabetes mellitus

Diabetes mellitus is a chronic disease with a high incidence worldwide and exclusive drug treatment has a limited eff...
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Essentials of Growth for the General Pediatrician

This article covers the fundamentals of infant, childhood, and adolescent growth and nutritional assessment, includin...
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Opinions on Ketogenic Diets Among Students and Academic Teachers at the University of Pécs, Hungary: A Cross-Sectional Survey

Background: The ketogenic diet (KD) is one of the most widely followed dietary approaches worldwide, frequently promo...
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Effects of Ketogenic Diet on Quality of Life in Parkinson Disease: An Integrative Review

Background/Aims: Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by the degeneration of d...
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Food in Migraine Management: Dietary Interventions in the Pathophysiology and Prevention of Headaches-A Narrative Review

Background: Migraine is a common, disabling neurological disorder with substantial genetic and environmental contribu...
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Efficacy and safety of ketogenic diets in drug-resistant epilepsy: a systematic review and meta-analysis

CONCLUSIONS: KDs and MADs are effective in reducing seizures in patients with drug-resistant epilepsy, especially in ...
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The ketogenic diet in Parkinson's disease: a potential therapeutic strategy

Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide, characterized by debilitatin...
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Effects of a two-week modified ketogenic diet on circulating lipoprotein subclasses, GDF15, and FGF21 in obese adults

CONCLUSION: The short-term MKD intervention significantly improved adiposity metrics while elevating GDF15 and reduci...
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Nourishing the Skin: A Review of Diet's Role in Hidradenitis Suppurativa

Hidradenitis suppurativa (HS) is a complex skin condition influenced by both genetic and environmental factors. Incre...
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Treatment Practices for Infantile Epileptic Spasms Syndrome: Consensus and Variation in Major Pediatric Epilepsy Centers

CONCLUSIONS: While there was broad consensus regarding first and second therapy treatment for IESS, variability exist...
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Energy status orchestrates YTHDF1 phase separation and tumorigenesis

Aberrant energy status impacts the initiation and progression of tumorigenesis, although the underlying mechanisms re...
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Development and validation of the iKETO-KNOW questionnaire: A tool for assessing knowledge of the ketogenic diet therapy

OBJECTIVE: Ketogenic dietary therapies (KDTs) are effective and safe alternatives for patients with drug-resistant ep...
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The Role of Various Types of Diets in the Treatments of Depressive Disorders

Depression is a prevalent and disabling psychiatric disorder, characterized by persistent disturbances in mood, cogni...
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Efficacy of Diet on Quality of life in Multiple Sclerosis (EDQ-MS): a study protocol for a randomized controlled clinical trial

BACKGROUND: The primary objective of this study is to evaluate the efficacy of two dietary interventions, time-restri...
[more]

Pros and cons of different dietary patterns for the treatment of metabolic dysfunction-associated steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) is becoming the most prevalent hepatic disorder, aff...
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Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer

Tumor-initiating cells (TICs) preferentially reside in poorly vascularized, nutrient-stressed tumor regions, yet how ...
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Deciphering the rules of disulfidptosis: a genome-wide signature for identifying disulfidptosis-related genes and analyzing hepatocellular carcinoma chemotherapy sensitivities

Disulfidptosis, a novel form of regulated cell death (RCD), represents a promising strategy for cancer therapy. Howev...
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β-Hydroxybutyrate enhances malate dehydrogenase 2 β-hydroxybutyrylation to alleviate hepatic steatosis in MASLD

Over the past three decades, the global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD...
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A Multidisciplinary Perspective on Semaglutide Treatment and Medical Nutrition Therapy in Obesity Management

PURPOSE OF REVIEW: This review explores the integration of semaglutide, a highly effective glucagon-like peptide-1 re...
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Efficacy and tolerability of a low-glycemic-index ketogenic diet in Angelman syndrome: findings from the DIANE study

AIM: This study evaluates the efficacy of a low-glycemic-index diet (LGID) in improving neurodevelopmental and sleep ...
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Ketogenic diet strategy in patients with sepsis: a multicentre prospective randomised interventional trial protocol

INTRODUCTION: Sepsis is defined as a dysregulated host response to infection, associated with high morbidity and mort...
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Higher dietary ketogenic ratio is associated with accelerated biological aging among US adults: analysis from NHANES 2005-2018

Ketogenic diet (KD) is widely prescribed for weight management in obese individuals, yet their potential impact on bi...
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Providing alternative fuel for the brain in anorexia nervosa: a review of the literature on ketones and their effects on metabolism and the brain

Recent genetic findings have highlighted the importance of metabolic factors in contributing to risk for anorexia ner...
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Diet as a Modulator of Gut Microbiota May Reduce Alzheimer's Disease Risk

The aging process, along with an inadequate diet and an inflammatory gut response resulting from dysbiosis, contribut...
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Low-carbohydrate ketogenic diet in Mc Ardle's disease: a single-blinded randomized controlled trial

Glycogenosis type 5 (GSD5, Mc Ardle's disease), the most common muscle glycogen storage disease characterized by exer...
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Exploring the Neurological Impacts of the Ketogenic Diet: A Comprehensive Review

CONCLUSION: Conclusions: The presented work provides an integrated compilation of currently available studies analyzi...
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The role and benefits of ketogenic diet in modulating inflammation in multiple sclerosis: A systematic review and meta-analysis

CONCLUSION: The ketogenic diet shows promise in improving inflammation, fatigue, depression, and quality of life in M...
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Breaking the metabolic-inflammatory vicious cycle in polycystic ovary syndrome: a comparative review of ketogenic and high-fat diets

Polycystic ovary syndrome (PCOS) is a multifactorial metabolic-endocrine disorder in women of reproductive age in whi...
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Ketogenic diet for alternating hemiplegia of childhood: Case report and literature review

RATIONALE: Alternating hemiplegia of childhood (AHC) is a serious and rare neurological disease caused by mutations i...
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The impact of very-low-calorie ketogenic diets on gut microbiota in individuals with obesity: a systematic review and meta-analysis

CONCLUSION: VLCKD appears to be a promising dietary intervention for modulating gut microbiota in individuals with ob...
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The therapeutic effects of ketogenic diet, lacosamide, and combination therapy in children with refractory epilepsy

CONCLUSIONS: KD and LCM combination therapy provides comprehensive benefits-superior seizure control, EEG normalizati...
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Quantifying endogenous and tracer-derived ketone bodies using a dual-label UHPLC-MS/MS method

Acetoacetate (AcAc) and β-hydroxybutyrate (βOHB) are ketone bodies involved in energy metabolism, particularly during...
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Effects of ketogenic diet on muscle mass, strength, aerobic metabolic capacity, and endurance in adults: a systematic review and meta-analysis

CONCLUSIONS: Among adult populations, KD can increase fat oxidation to modify muscle metabolism, while no significant...
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Clinical and radiological evaluation of children with hemimegalencephaly and epilepsy: A single-center study

CONCLUSION: Hemimegalencephaly represents a challenging etiology in refractory epilepsy of early childhood. Given the...
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The effectiveness of the ketogenic diet in treating refractory epilepsy: A study of different seizure forms

The objective of this study was to compare the efficacy of the ketogenic diet (KD) in patients with refractory epilep...
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Screening of metabolic markers in pediatric epilepsy disorders

CONCLUSION: This study identified and validated peripheral blood metabolites in children with epilepsy. OA was found ...
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TMAO Accumulation Induced by Hyperglycemia Triggers Endoplasmic Reticulum Stress in the Mouse Liver

Excessive carbohydrate intake is a well-established driver of metabolic dysfunction, but its specific role in perturb...
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Therapeutic effectiveness of low-calorie ketogenic diet on body composition and biochemical parameters in polycystic ovary syndrome - An intervention study

Introduction: the effectiveness of the ketogenic diet (KD) as a therapeutic approach for managing weight, hormonal, a...
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The Ketogenic Diet Through a Metabolomic Lens: Biochemical Pathways, Therapeutic Applications, and Analytical Challenges

CONCLUSIONS: Metabolomic analysis provides critical insights into the multifaceted effects of the KD, supporting its ...
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Exploring the Anti-Inflammatory Potential of a Mediterranean-Style Ketogenic Diet in Women with Lipedema

Background/Objectives: Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulati...
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Carbohydrate-restricted diet types and macronutrient replacements for metabolic health in adults: A meta-analysis of randomized trials

CONCLUSIONS: CRDs, particularly LCDs and MCDs with mixed macronutrient replacements, confer significant metabolic ben...
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Ketogenic diet inhibits glioma progression by promoting gut microbiota-derived butyrate production

The ketogenic diet (KD) is a potential therapeutic strategy for glioma; however, the underlying mechanisms remain unc...
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Advances and Clues of Nutritional Adjuvant Therapy for Charcot-Marie-Tooth Disease

Charcot-Marie-Tooth disease (CMT) is an inherited peripheral neuropathy with significant genetic heterogeneity and cl...
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Efficacy of ketogenic diet therapy for pediatric drug-resistant epilepsy with monogenic etiology: A single-arm meta-analysis

CONCLUSIONS: The present meta-analysis revealed the efficacy of KDT in the treatment of genetic epilepsies, particula...
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Caffeine enhances performance regardless of fueling strategy; however, high carbohydrate availability is associated with improved training speeds compared with ketogenic diet

The purpose of this study was to confirm reduced training metrics previously associated with a ketogenic low-carbohyd...
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